DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5568 and pdgy

DIOPT Version :9

Sequence 1:	NP_647992.1	Gene:	CG5568 / 38658	FlyBaseID:	FBgn0035641	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	559	Identity:	133/559 - (23%)
Similarity:	234/559 - (41%)	Gaps:	69/559 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 GGEKRSLFS----PDLSIGEIIFQQMERNAMLTAQISVTENTELTWKDIQ-TNAMKVASYMRKLG 85
            |..|.|.|.    |::.:.|.:::..::....||.:.|..:.:.|:..:: .:|........|..
  Fly    60 GYYKTSPFDPVTIPNVPLHEYVWRDFKKWERRTAAVCVITDRQYTFAQMRDASAAFAVRLQTKFN 124

  Fly    86 LEQGDFVGV------------IGRLTTHLTALAYACFFNGTPYHALHTEYEQSAIERLFGITKPR 138
            |::.|.:.:            :|.:...||.         |..:.::|..|   |.|....:..:
  Fly   125 LQKPDVLAICLPNLPEYPIATLGAIEAGLTV---------TTVNPVYTPDE---IARQLTFSGAK 177

  Fly   139 LIFCDGDEFEKVQAATK--GLQVQIVTMRNH-----PAGILRIQDILTTPVEMNFRPVRLKD--- 193
            .:......|..:..|:|  |.|:.|..:|..     |.|.:...::.:|      :.||.:|
  Fly   178 FLVGTVSGFATLSQASKLVGRQIPIAVVRTSAEEALPEGAIDFSELTST------QNVRYEDLKA 236

  Fly   194 ----GTDQLLAILSSSGTSGLPKAVTI------SNSHQIIGSFLPVDSSIIQYNPNTLDWASGIT 248
                ..|.::.:..||||:||||.|.:      ||..|:..| ||:|   :....|||.......
  Fly   237 PKEASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQAS-LPLD---LMGPQNTLPGVLPFF 297

  Fly   249 MTINAAVFSLTSIIEDCD------FDPANLCGLIEKYRISMVFVSSSQLAMLSNCPEFYAADLSS 307
            ......|..|:.:.:.|.      |.|.:....::||:.|::.:.......:.|.|:........
  Fly   298 HIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQETAPH 362

  Fly   308 VKYFFYGGSNCSLEVQNKIRSRLSNECVNFSYTLTELNSPGCLNFNFDEKPNSVGRPVRGIQIKI 372
            :|....|.:........:..::..|......|.:||.:....|....::...|.|......:.||
  Fly   363 LKVVMSGAAPIGQHDVERFLNKFPNTVFKQGYGMTEASPVVLLTPEGNKVYASTGVLPASTEAKI 427

  Fly   373 VNELG---EAQGPNVVGEICFNNGQKWPGYYKNPEETKKMQDSENWFHTGDLGYMDEDGYLFIID 434
            |...|   :..||...||:|....|...||..|.|..:......||..:||:.:.||||..:|.|
  Fly   428 VPLDGSDAKGVGPRTTGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDEDGLFYITD 492

  Fly   435 RLKDMLKYQTIMYYPSEIESVIAEMPNVVEACVFGIWDPVYGDKAAASVVKKQGTQLEAQDVVEY 499
            |:|:::|.:.....|:|:|:|:.:.|.::||.||||.....|:...|.||.:||.:..|:::..|
  Fly   493 RMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVLRQGEKASAEEISAY 557

  Fly   500 VRKRIPAKFKQLNGGALIVDHIIQSGNRKANRAATKAEF 538
            |.:|: |.:|:|.||.:.||.:.::...|..|...|.:|
  Fly   558 VAERV-AHYKKLEGGVIFVDEVPKNPTGKILRRELKEKF 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	129/546 (24%)
CG5568	NP_647992.1	Firefly_Luc_like	55..530	CDD:213279	123/516 (24%)
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	127/540 (24%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	121/510 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452139
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850