DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5568 and Slc27a4

DIOPT Version :9

Sequence 1:NP_647992.1 Gene:CG5568 / 38658 FlyBaseID:FBgn0035641 Length:545 Species:Drosophila melanogaster
Sequence 2:NP_001094176.1 Gene:Slc27a4 / 311839 RGDID:1307383 Length:643 Species:Rattus norvegicus


Alignment Length:542 Identity:121/542 - (22%)
Similarity:201/542 - (37%) Gaps:134/542 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    47 MERNAMLTAQISVTENTELTWKDIQTNAMKVASYMRKLGLEQG-----------DFVGV-IGR-- 97
            :.|:...||.|....||..|::.:...:..||::::..||..|           :|||: :|.  
  Rat    84 VRRHPDKTALIFEGTNTHWTFRQLDDYSSSVANFLQARGLVSGNVVALFMENRNEFVGLWLGMAK 148

  Fly    98 -------LTTHL----------TALAYACFFNGTPYHALHTEYEQSAIERLFGITKPRL-IFCDG 144
                   :.|:|          |:.|.|..|...         ..||:..:..|..|.| :||.|
  Rat   149 LGVEAALINTNLRRDALRHCLDTSKARALIFGSE---------MASAVYEIQAILDPTLTLFCSG 204

  Fly   145 D-EFEKVQAATKGLQVQIVTMRNHPAGILRIQDILTTPVEMNFRPVRLKDGTDQLLAILSSSGTS 208
            . |...|.|.|:.|.   ..:.:.|..:..|.|               |..||:|..|. :|||:
  Rat   205 SWEPSTVPANTEHLD---PLLEDAPKHLPSIPD---------------KGFTDKLFYIY-TSGTT 250

  Fly   209 GLPKAVTISNSH-----------------QIIGSFLPVDSS---IIQYNPNTLDWASGITMTINA 253
            |||||..:.:|.                 .|:...||:..|   |:......|   .|:|:.|..
  Rat   251 GLPKAAIVVHSRYYRMAALVYYGFRMRPDDIVYDCLPLYHSAGNIVGIGQCVL---HGMTVVIRK 312

  Fly   254 AVFSLTSIIEDCDFDPANLCGLIEKYRISMVFVSSSQLAMLSNCPEFYAADLSSVKYFFYGGSNC 318
            . ||.:...:||           .||..::|.........|.|.|...|.....|:...  |:..
  Rat   313 K-FSASRFWDDC-----------IKYNCTIVQYIGELCRYLLNQPPREAESRHKVRMAL--GNGL 363

  Fly   319 SLEVQNKIRSRLSNECVNFSYTLTELNSPGCLNFNFDEKPNSVG---------RPVRGIQIKIVN 374
            ...:.....||.....|...|..||.|   |...|||.:..:.|         .|:|.::   ||
  Rat   364 RQSIWTDFSSRFHIPQVAEFYGATECN---CSLGNFDSQVGACGFNSRILSFVYPIRLVR---VN 422

  Fly   375 E--LGEAQGPN-------------VVGEICFNNG-QKWPGYYKNPEETKKM-----QDSENWFHT 418
            |  :...:||:             :||.|...:. :::.||.......||:     :..:..:.|
  Rat   423 EDTMELIRGPDGVCIPCQPGQPGQLVGRIIQQDPLRRFDGYLNQGANNKKIASDVFKKGDQAYLT 487

  Fly   419 GDLGYMDEDGYLFIIDRLKDMLKYQTIMYYPSEIESVIAEMPNVVEACVFGIWDPVYGDKAAASV 483
            ||:..|||.|||:..||..|..:::......:|:|..::.:..:.:..|:|:..|....:|..:.
  Rat   488 GDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLQMADVAVYGVEVPGAEGRAGMAA 552

  Fly   484 VKKQGTQLEAQDVVEYVRKRIP 505
            |....:..:.:...:.::|.:|
  Rat   553 VASPTSNCDLESFAQTLKKELP 574

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5568NP_647992.1 CaiC 35..540 CDD:223395 121/542 (22%)
Firefly_Luc_like 55..530 CDD:213279 119/534 (22%)
Slc27a4NP_001094176.1 PRK08279 75..643 CDD:236217 121/542 (22%)
hsFATP4_like 99..608 CDD:213305 117/527 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166343024
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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