DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5568 and Acsm2

DIOPT Version :9

Sequence 1:NP_647992.1 Gene:CG5568 / 38658 FlyBaseID:FBgn0035641 Length:545 Species:Drosophila melanogaster
Sequence 2:NP_653349.1 Gene:Acsm2 / 246263 RGDID:708383 Length:572 Species:Rattus norvegicus


Alignment Length:510 Identity:114/510 - (22%)
Similarity:199/510 - (39%) Gaps:57/510 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 ELTW--KDIQTNAMKVASYMR-KLGLEQGDFVGVIGRLTTHLTALAYACFFNGTPYHALHTEYEQ 125
            ||.|  :::...:.:.|:.:. ..||::||.|.|:.........:...|..:|..:....|:.:.
  Rat    78 ELKWNFRELSEISKQTANVLTGACGLQRGDRVAVVLPRVPEWWLVTLGCMRSGLVFMPGTTQMKS 142

  Fly   126 SAIERLFGITKPRLIFCDGDEFEKVQAATKG---LQVQIVTMRNHPAGILRIQDIL--TTPVEMN 185
            :.|......:|.|.|....:..::|.|....   |:::::....:..|.|..:.:|  .:|:...
  Rat   143 TDILYRLQSSKARAIVAGDEVVQEVDAVAPDCSFLKIKLLVSEKNREGWLNFKALLKDASPIHQC 207

  Fly   186 FRPVRLKDGTDQLLAILSSSGTSGLPKAVTISNSHQIIGSFLPVDSSIIQYNPNTLDWASGITMT 250
            ...|     :.:..||..:|||||.||..  .:||..:|....:|:......|:...|....|..
  Rat   208 VETV-----SQESAAIYFTSGTSGPPKMA--EHSHCSLGLKAKMDAGWTGLGPSDTMWTISDTGW 265

  Fly   251 INAAVFSLTS--IIEDC-------DFDPANLCGLIEKYRISMVFVSSSQLAMLSNCPEFY----A 302
            |...:.|...  ::..|       .|||..:..::..|.|:          .|...|..|    .
  Rat   266 ILNILGSFLEPWVLGTCIFVHLLPKFDPQTVLKVLSSYPIN----------TLLGAPLIYRMLLQ 320

  Fly   303 ADLSSVKY-----FFYGGSNCSLEVQNKIRSRLSNECVNFSYTLTELNSPGCLNFNFDEKPNSVG 362
            .||||.|:     .|.||.....|.....:::...| :...|..||......::.....||..:|
  Rat   321 QDLSSYKFPHLHSCFSGGETLLPETLESWKAKTGLE-IREIYGQTETGITCRVSRTMKVKPGYLG 384

  Fly   363 RPVRGIQIKIVNELGEAQGPNVVGEICFNNGQKWP-----GYYKNPEETKKMQDSENWFHTGDLG 422
            ..:....:::::|.|....|...|::........|     ||..||::|:.....:.|. .||.|
  Rat   385 TAIVPYDVQVIDEQGNVLPPGKEGDMALRVKPIRPIGMFSGYVDNPKKTQANIRGDFWL-LGDRG 448

  Fly   423 YMDEDGYLFIIDRLKDMLKYQTIMYYPSEIESVIAEMPNVVEACVFGIWDPVYGDKAAASVVKKQ 487
            ..|.:||...:.|..|::........|||:|:.:.|.|.|||..|....||:..:...|.||...
  Rat   449 IKDTEGYFHFMGRTDDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPIRREVVKAFVVLAP 513

  Fly   488 GTQLEAQD-----VVEYVRKRIPAKFKQLNGGALIVDHIIQSGNRKANRAATKAE 537
            ......||     :.|:| |.:.|.:|.......::| :.::...|..||..:|:
  Rat   514 EFLSHDQDQLTKVLQEHV-KSVTAPYKYPRKVEFVLD-LPKTITGKIERAKLRAK 566

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5568NP_647992.1 CaiC 35..540 CDD:223395 114/510 (22%)
Firefly_Luc_like 55..530 CDD:213279 111/501 (22%)
Acsm2NP_653349.1 AFD_class_I 40..568 CDD:302604 114/510 (22%)
Acs 40..565 CDD:223442 113/507 (22%)
Coenzyme A binding. /evidence=ECO:0000250 469..471 0/1 (0%)
Coenzyme A binding. /evidence=ECO:0000250 540..542 0/1 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D683933at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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