DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5568 and Acsm4

DIOPT Version :9

Sequence 1:	NP_647992.1	Gene:	CG5568 / 38658	FlyBaseID:	FBgn0035641	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_848501.1	Gene:	Acsm4 / 233801	MGIID:	2681844	Length:	580	Species:	Mus musculus

Alignment Length:	506	Identity:	120/506 - (23%)
Similarity:	205/506 - (40%)	Gaps:	81/506 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 ELTW--KDIQTNAMKVASYMRK-LGLEQGDFVGVIGRLTTHLTALAYACFFNGTPYHALHTEYEQ 125
            |:.|  :::.:.:.|.|:.:.| .||::||.|.||.........:..||...|..:.....:..:
Mouse    86 EVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLINVACMRTGLVFMPGTIQLTR 150

  Fly   126 SAIERLFGITKPRLIFCDGD---EFEKVQAATKGLQVQIVTMRNHPAGILRIQDILTTPVEMNFR 187
            ..|......:|.:.|....:   ..:.:.:....|:.:::...:|..|.|..|::|.:..|.:
Mouse   151 KDILYRLQASKAKCIVASEEVAPAVDSIVSECPSLKTKLLVSPHHWDGWLNFQELLQSASEEH-- 213

  Fly   188 PVRLKDGTDQLLAILSSSGTSGLPKAVTISNSHQIIG------SFLPVDSSIIQYNPNTLDWASG 246
             ..::.|:.:.:||..:|||:|.||....|.....||      .:|.:.||.|.:|.:...|
Mouse   214 -NCVETGSQEPMAIYFTSGTTGSPKMAQHSQGSLGIGYTLCGRYWLDLTSSDIMWNMSDTGW--- 274

  Fly   247 ITMTINAAVFSLTS---------IIEDCDFDPANLCGLIEKYRISMVFVSSSQLAMLSNCPEFYA 302
                |.||:.|:.|         :.....||.......:..|.|:.:..:.:...||.. .:...
Mouse   275 ----IKAAIGSVFSTWLRGACVFVHRMAQFDTDIFLDTLTTYPITTLCSAPTVYRMLVQ-KDLKR 334

  Fly   303 ADLSSVKYFFYGGSNCSLEVQNKIRSRLSNECVNFSYTLTELNSPGCLNFNFDE-KPNSVGRPVR 366
            .....:::...||...:.||..:.:.:...|... .|..||:... |.|...:. ||.|:|:.|.
Mouse   335 YQFKRLRHCLTGGEPLNPEVLEQWKMQTGLELYE-GYGQTEVGII-CANRKGEAIKPGSMGKGVV 397

  Fly   367 GIQIKIVNELGEAQGPNVVGEI----------CFNNGQKWPGYYKNPEETKKMQDS---ENWFHT 418
            ...::|::|.|........|||          ||     :..|..|||:|    |:   .|::.|
Mouse   398 PYDVQIIDENGNILPSGKEGEIALRLKSDRPFCF-----FSEYVDNPEKT----DATIRRNFYVT 453

  Fly   419 GDLGYMDEDGYLFIIDRLKDMLKYQTIMYYPSEIESVIAEMPNVVEACVFGIWDPVYGDKAAASV 483
            ||.|.||:|||.:.:.|..|::........|.|:||.:.|.|.|||:.|....||:.|:...|.:
Mouse   454 GDRGVMDDDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFI 518

  Fly   484 V--------KKQGTQLEAQD-------------VVEYVR---KRIPAKFKQ 510
            |        .::....|.||             .||:|:   |.|..|.|:
Mouse   519 VLAAPYKCSNREKLTAELQDHVKNSTAPYKYPRKVEFVQELPKTITGKIKR 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	120/506 (24%)
CG5568	NP_647992.1	Firefly_Luc_like	55..530	CDD:213279	120/506 (24%)
Acsm4	NP_848501.1	MACS_euk	48..577	CDD:213294	120/506 (24%)
Acsm4	NP_848501.1	Acs	49..576	CDD:223442	120/506 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920