Protein Alignment CG5568 and ACSL6

DIOPT Version :10

• Sequence 1: NP_647992.1
• Gene: CG5568 / 38658
• FlyBaseID: FBgn0035641
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_056071.2
• Gene: ACSL6 / 23305
• HGNCID: 16496
• Length: 722
• Species: Homo sapiens
• Alignment Length: 670
• Identity: 145/670 - (21%)
• Similarity: 226/670 - (33%)
• Gaps: 195/670 - (29%)

  Fly    25 SGGEKRSLF--SPDL-----SIGEIIFQQMERNAMLTAQISVTENTE-------------LTWKD 69
            |||.:||:.  .|.|     .....::|...|.      :|::.|..             |::::
Human    92 SGGARRSVIGSGPQLLTHYYDDARTMYQVFRRG------LSISGNGPCLGFRKPKQPYQWLSYQE 150

  Fly    70 IQTNAMKVASYMRKLGLEQ-------GDFVGVIGRLTTHLTALAYACFFNGTPYHALHTEYEQSA 127
            :...|..:.|     ||.|       ..|:||..:.......:..||:........|:......|
Human   151 VADRAEFLGS-----GLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGA 210

  Fly   128 IERLFGITKPRLIFCDGDE-----FEKVQ-AATKGLQVQIVTM---------RNHPAGIL--RIQ 175
            |..:........:..|..:     .|.|: ..|.||:: |:.|         |....|::  .:|
Human   211 IRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKL-IILMDPFEEALKERGQKCGVVIKSMQ 274

  Fly   176 DILTTPVEMNFRPVRLKDGTDQLLAILSSSGTSGLPKAVTISNSHQI--IGSFLPVDSSIIQYNP 238
            .:.....|.:..||  ....|.|..:..:|||:|.||...:::.:.:  ...||.|..|  |:.|
Human   275 AVEDCGQENHQAPV--PPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTES--QWAP 335

  Fly   239 NTLD--------------------WASG-------------------ITMTINAAVFSLTSIIED 264
            ...|                    :..|                   :..||...|..|.:.:.|
Human   336 TCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYD 400

  Fly   265 CDFDPANL-------------------CGLIEKYRI-SMVFVSSSQLAMLSNCPEFYAADLSSVK 309
            ..|..||.                   .|:|....| ..:|.:..| |.|..|          |:
Human   401 KIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQ-ASLGGC----------VR 454

  Fly   310 YFFYGGSNCSLEVQNKIRSRLSNECVNFSYTLTE------LNSPGCLNFNFDEKPNSVGRPVRGI 368
            ....|.:..|..|...:|:.|..: |...|..||      ..:||      |.....||.|:...
Human   455 MIVTGAAPASPTVLGFLRAALGCQ-VYEGYGQTECTAGCTFTTPG------DWTSGHVGAPLPCN 512

  Fly   369 QIKIVN--EL------GEAQGPNVVGEICFNNGQKWPGYYKNPEETKKMQDSENWFHTGDLGYMD 425
            .||:|:  ||      ||       ||||......:.||.|:|:.||:..||:.|.||||:|...
Human   513 HIKLVDVEELNYWACKGE-------GEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWL 570

  Fly   426 EDGYLFIIDRLKDMLKYQTIMYY-PSEIESVIAEMPNVVEACVFG-----------IWDP----- 473
            ..|.|.||||.|.:.|.....|. |.:||::......|.:..|.|           :.||
Human   571 PAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPS 635

  Fly   474 ---------VYGDKAAASVVKKQGTQLEAQDVVEYVRKRIPAKFKQLNGGALIVDHI-IQSG--- 525
                     .|.|......:||    ...:|:|...::.....|:|:....:..|.. :|:|
Human   636 WAQKRGIEGTYADLCTNKDLKK----AILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLT 696

  Fly   526 -NRKANRAATKAEFLRIMEK 544
             ..||.|...:..|.:.:|:
Human   697 PTLKAKRPELREYFKKQIEE 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	Firefly_Luc_like	55..528	CDD:341237	131/615 (21%)
ACSL6	NP_056071.2	LC-FACS_euk	141..719	CDD:341250	134/615 (22%)