Protein Alignment CG5568 and ACSL4

DIOPT Version :9

• Sequence 1: NP_647992.1
• Gene: CG5568 / 38658
• FlyBaseID: FBgn0035641
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_024308119.1
• Gene: ACSL4 / 2182
• HGNCID: 3571
• Length: 717
• Species: Homo sapiens
• Alignment Length: 642
• Identity: 128/642 - (19%)
• Similarity: 227/642 - (35%)
• Gaps: 167/642 - (26%)

  Fly     9 SPFKTRNTFDENLKIWSGGEKR---------SLFSPDLSIG--EIIFQ--QMERNAMLTAQISVT 60
            ||:::...||....|...|...         |.|....|:|  ||:.:  :|:.|..:..::.:.
Human    63 SPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILG 127

  Fly    61 ENTELTWKDIQTNAMKVASYMRKLGLEQGDFVGVIGRLTTHLTALAYACFFNGTPYHALHTEYEQ 125
            ....:.:.::........|.:..|||:..:.:.:...........|..||....|...|:....:
Human   128 NYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGK 192

  Fly   126 SAI-------ERLFGITKPRL------------------IFCDGDEFEKVQAATKGLQVQIVTMR 165
            .|:       |..:.||...|                  |:.|.....|.: ..:|.::.  :|:
Human   193 EAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAE-YPEGFEIH--SMQ 254

  Fly   166 NHPAGILRIQDILTTPVEMNFRPVRLKDGTDQLLAILSSSGTSGLPKAVTISNSHQIIG------ 224
            :       ::::.:.|..:...|.|  .....:..::.:||::|.||.|.:.:|:.|.|
Human   255 S-------VEELGSNPENLGIPPSR--PTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCE 310

  Fly   225 ------------SFLPV--------DSSIIQY-------NPNTL-DWASGITM-----------T 250
                        .:||:        :.|...|       :|.|| |.:|.|..           |
Human   311 RIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPT 375

  Fly   251 INAAV--------FSLTSIIEDCDFDPANLCGLIEKYRISMVFVSSSQLAMLSNCPEFYAADL-- 305
            :.|||        .::.|.:::.::....|..:...|::..  :.....|.|.|...|.....
Human   376 LMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQ--IKKGYDAPLCNLLLFKKVKALL 438

  Fly   306 -SSVKYFFYGGSNCSLEVQNKIRSRLSNEC----VNFSYTLTELNSPGCLNFNFDEKPNSVGRPV 365
             .:|:....||:..|.:..     |..|.|    :...|.|||....|.:....|.....||.|:
Human   439 GGNVRMMLSGGAPLSPQTH-----RFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPL 498

  Fly   366 RGIQIKI---------VNELGEAQGPNVVGEICFNNGQKWPGYYKNPEETKK----MQDSENWFH 417
            ...:||:         :|:     .||..|||.........||:||.|:|.:    .::.:.||.
Human   499 ICCEIKLKDWQEGGYTIND-----KPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFC 558

  Fly   418 TGDLGYMDEDGYLFIIDRLKDMLKYQTIMYYP-SEIESVIAEMPNVVEACVF------------- 468
            |||:|....||.|.||||.||::|.|...|.. .::|:.:...|.:...|.|
Human   559 TGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVV 623

  Fly   469 ----------------GIWDPVYGDKAAASVVKKQGTQLEAQDVVEYVRKRIPAKFK 509
                            |.|..:..:.|..:.:.|:  ..||.:.::..|..||.|.:
Human   624 PNQKRLTLLAQQKGVEGTWVDICNNPAMEAEILKE--IREAANAMKLERFEIPIKVR 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	120/607 (20%)
		Firefly_Luc_like	55..530	CDD:213279	114/583 (20%)
ACSL4	XP_024308119.1	LC-FACS_euk	127..714	CDD:213293	114/578 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148965
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930