Protein Alignment CG5568 and mec-18

DIOPT Version :10

• Sequence 1: NP_647992.1
• Gene: CG5568 / 38658
• FlyBaseID: FBgn0035641
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_508731.3
• Gene: mec-18 / 180701
• WormBaseID: WBGene00003179
• Length: 638
• Species: Caenorhabditis elegans
• Alignment Length: 572
• Identity: 133/572 - (23%)
• Similarity: 234/572 - (40%)
• Gaps: 101/572 - (17%)

  Fly    38 SIGEIIFQQMERNAMLTAQISVTENTELTWKDIQTNAMKVASYMRKLGLEQGDFVGVIGRLTTHL 102
            |..:..|.::..:....|.:.|....:..:.:|:......|:.:::|.:..|..|.||...|...
 Worm    18 SFHDYFFSKISAHGSNLAIVDVDSGKQWRYSEIRNWCEMCATRLKELQVTSGSRVAVITGTTGQA 82

  Fly   103 TALAYACFFNGTPYHALHTEYEQSAIERLFGITKPRLIFCDGDEFEKVQAATKGLQVQIVTMRNH 167
            ..:..||...|....|::.......|..|..:::...:..:....:|.....:..|::......|
 Worm    83 IFVHLACSIIGCSAVAVNGWNAVDEIWTLVDLSEATHLIVENQFMQKADDVRRKAQMRGGGRIKH 147

  Fly   168 PAGILRIQDILTT-------------------PV--EMNFRPVRLKDGTDQLLAILSSSGTSGLP 211
               :.:|:|:||.                   |:  ||:...:.|.....:.:|.|:|      |
 Worm   148 ---VRQIEDVLTAERINVDSARKRSIDVKQKPPLVKEMSLAKINLTPVLPEDIADLTS------P 203

  Fly   212 KAVTISNSHQIIGSFLPVDSSIIQ-------------YNPNTLDWASGITMTINAAVFSLTSIIE 263
            .:.....|.::.|.   |:||::.             .||..:.:.||.|....||..|..|:|.
 Worm   204 VSEVSGQSKELNGD---VESSVVDSEEVQTPIQQVSGQNPLLILFTSGTTGLAKAAELSHRSLII 265

  Fly   264 DCD------FDP-------------ANLCGLIEKY-----------------RISMVFVSSSQLA 292
            :..      :.|             |::.|::..|                 |:.|..:.::|:.
 Worm   266 NIQQISLPLYGPVQTKERFLLPLSIAHIYGIVSAYYALINGASLYLISKQSNRLFMETLVNNQIN 330

  Fly   293 MLSNCP-------------EFYAADLSSVKYFFYGGSNCSLEVQNKIRSRLSNECVNFSYTLTEL 344
            ::...|             ::...:|.||   ...|:.........::|||:.:....|:.:|||
 Worm   331 VMHITPAIVHWMATDAIVDDYKTPNLRSV---LCAGAPIDSNSAAAMKSRLNIKDFRQSFGMTEL 392

  Fly   345 NSPGCLNFNFDEKPNSVGRPVRGIQIKIVN-ELGEAQGPNVVGEICFNNGQKWPGYYKNPEETKK 408
            .....::...|||..|||.|:.|:..|:|| |..:...|...|:|.....|..|.|||||:.|.:
 Worm   393 GGICTMSPYLDEKIESVGNPLPGMLFKVVNWETKQLCLPRQPGQIIVLGPQVSPCYYKNPKATSE 457

  Fly   409 MQDSENWFHTGDLGYMDEDGYLFIIDRLKDMLKYQTIMYYPSEIESVIAEMPNVVEACVFGIWDP 473
            :.|:..:..|||.|:.||.|.::::||:||::|.:..|..|||:|.|:.....:.:..|.|..|.
 Worm   458 LFDATGFVKTGDAGFYDEVGRIYVLDRIKDIIKCKGTMICPSEVELVLRAHAGIDDCAVVGRQDH 522

  Fly   474 VYGDKAAASVVKK-QGTQLEAQDVVEYVRKRIPAKFKQLNGGALIVDHIIQS 524
            |.|:..||.|||. |...|.:.:|.:||..:| |.||:|.||...:..|.:|
 Worm   523 VTGEVPAAFVVKNAQHPLLASAEVRQYVSGKI-ATFKELRGGVFFISEIPRS 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	Firefly_Luc_like	55..528	CDD:341237	131/555 (24%)
mec-18	NP_508731.3	Firefly_Luc_like	35..579	CDD:341237	131/555 (24%)