DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5568 and Acsbg1

DIOPT Version :9

Sequence 1:	NP_647992.1	Gene:	CG5568 / 38658	FlyBaseID:	FBgn0035641	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_599216.1	Gene:	Acsbg1 / 171410	RGDID:	708557	Length:	721	Species:	Rattus norvegicus

Alignment Length:	583	Identity:	127/583 - (21%)
Similarity:	217/583 - (37%)	Gaps:	173/583 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 AMKVASYMRKLGLEQGDFVGVIGRLTTHLTALAYACFFNGTPYHALHTEYEQSAIERLFGITKPR 138
            |.|||....|||||:...|.::|..:......|....|.|.....::|.....|.:.:....:..
  Rat   139 ARKVAKGFLKLGLERAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAHDCRAN 203

  Fly   139 LIFCDGD-EFEKVQAATKGL-QVQIVTMRNHP-----AGILRIQDILTTPVEMNFRPVRLKDG-- 194
            :|..|.. :.||:....|.| .::.|.:...|     |.:..:::::....|:   |....|.
  Rat   204 VIVVDTQKQLEKILKIWKDLPHLKAVVIYQEPPPKKMANVYTMEELIELGQEV---PEEALDAII 265

  Fly   195 ----TDQLLAILSSSGTSGLPKAVTISNSH---------------------QIIGSFLPVDSSII 234
                .:|...::.:|||:|.||.|.:|..:                     :::.|:||:.....
  Rat   266 DTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIQPAEVQQEVVVSYLPLSHIAA 330

  Fly   235 Q-YNPNT-LDWASGITMTINAAVFSLTSIIEDCDFDPANLCGLI-------------------EK 278
            | |:..| :.|.:.:                 |..||..|.|.:                   ||
  Rat   331 QIYDLWTGIQWGAQV-----------------CFADPDALKGTLVNTLREVEPTSHMGVPRVWEK 378

  Fly   279 Y---------------RISMVFVSSSQLAMLSNCPEFYAADLSSVKYF----------------- 311
            .               |..:::..|..|.....||.      :.:|.|
  Rat   379 IMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPS------NDLKPFTSRLADYLVLARVRQAL 437

  Fly   312 --------FYGGSNCSLEVQN-----KIRSRLSNECVNFSYTLTELNSPGCLNFNFDEKPNSVGR 363
                    |||.:..:.|.|.     .||       :...|.|:|...|..::..::.:..|.||
  Rat   438 GFAKCQKNFYGAAPMTAETQRFFLGLNIR-------LYAGYGLSESTGPHFMSSPYNYRLYSSGR 495

  Fly   364 PVRGIQIKIVNELGEAQGPNVVGEICFNNGQKWPGYYKNPEETKKMQDSENWFHTGDLGYMDEDG 428
            .|.|.::|:||:  :|.|   :||||......:.||....::|.:..|||.|.||||:|.:|:||
  Rat   496 VVPGCRVKLVNQ--DADG---IGEICLWGRTIFMGYLNMEDKTHEAIDSEGWLHTGDMGRLDDDG 555

  Fly   429 YLFIIDRLKDML---KYQTIMYYPSEIESVIAEMPNVVEACVFG--------------IWDPVYG 476
            :|:|..|||:::   ..:.:...|.| |:|..|:|.:..|.:.|              ..:|...
  Rat   556 FLYITGRLKELIITAGGENVPPVPIE-EAVKMELPIISSAMLIGDQRKFLSMLLTLKCTLNPETS 619

  Fly   477 D------KAAASVVKKQGTQLEAQDVVEYVRKRIPAKFKQLNGGALIVDHIIQSGNRKANRAA 533
            :      :.|....::.|:  :|..|.|.|.::..|.::.::.|       ||..|  ||.||
  Rat   620 EPTDNLTEQAVEFCQRVGS--KASTVSEIVGQKDEAVYQAIHEG-------IQRVN--ANAAA 671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	127/583 (22%)
CG5568	NP_647992.1	Firefly_Luc_like	55..530	CDD:213279	123/578 (21%)
Acsbg1	NP_599216.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64
Acsbg1	NP_599216.1	ACSBG_like	122..716	CDD:341256	127/583 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342861
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930