DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5568 and acsl2

DIOPT Version :9

Sequence 1:	NP_647992.1	Gene:	CG5568 / 38658	FlyBaseID:	FBgn0035641	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	XP_002663285.4	Gene:	acsl2 / 100332846	ZFINID:	ZDB-GENE-130530-851	Length:	715	Species:	Danio rerio

Alignment Length:	556	Identity:	116/556 - (20%)
Similarity:	195/556 - (35%)	Gaps:	161/556 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 LTWKDIQTNAMKVASYMRKLGLEQG--DFVGVIGRLTTHLTALAYACFFNGTPYHALHTEYEQSA 127
            :::.::...|..:.|.:...|.:..  .:||:..:..........||:   |...||...|:...
Zfish   138 ISYTEVAERAQVLGSGLLAKGCKPNPQQYVGIYAQNRPEWVIAELACY---TFSMALVPLYDTLG 199

  Fly   128 IE---RLFGITKPRLIFCDGDE------FEKVQAATKGLQVQI--------VTMRNHPAG--ILR 173
            ||   .:..:.:..::.||.::      ..|.:..|..|...:        :..|....|  ||:
Zfish   200 IEAMVHILNLAEISMVICDKEDKAESLLRNKEKGVTPSLSCLVLFNPFSAALLDRGRKCGMEILQ 264

  Fly   174 IQDILTTPVEMNFRPVRLKDGTDQLLAILSSSGTSGLPKAVTISNSHQIIGSFLPVDSSIIQYNP 238
            :..|:....|....||..|  ...|..:..:|||:|.||...|::     |:.....||:|:
Zfish   265 LSQIMDLGRENLKPPVPPK--PQDLAVVCFTSGTTGKPKGAMITH-----GNIASNTSSVIK--- 319

  Fly   239 NTLDWASGITMTINAAVFSLTSIIEDCDFDPANLCGLIEK-YRISMVFVSSSQLAMLSNCPEFYA 302
                        |....|.:..  ||.......|..:.|: .::|| |...:::.       ||.
Zfish   320 ------------ILEGYFVIRQ--EDVSISYLPLAHMFERMIQVSM-FCHGARVG-------FYQ 362

  Fly   303 ADLS-------SVKYFFYGG-----------------------------------------SNCS 319
            .|:|       ::|..|:.|                                         .|.|
Zfish   363 GDISLLMDDIKTLKPTFFPGVPRLLNRIYDKILGSVTSPLKRVLLHYAVRRKQAELSSGVVRNNS 427

  Fly   320 L---EVQNKIRSRLSNECVNFSYTLTELNSP----------GCLNFN----------------FD 355
            |   .:.|||::.|... :.|..|.:...||          |||.|.                .|
Zfish   428 LWDRLIFNKIQASLGGN-LRFILTASAPISPAVLSFLRATLGCLIFEGYGQTECTAGCTFSMPGD 491

  Fly   356 EKPNSVGRPVRGIQIKIVN--------ELGEAQGPNVVGEICFNNGQKWPGYYKNPEETKKMQDS 412
            .....||.|:....:|:.:        :.||       ||||......:.||.|:.|.|.:..|:
Zfish   492 WSAGHVGAPLPCAMVKLTDIPDMNYYAKNGE-------GEICIRGPSVFRGYLKDEERTAEALDT 549

  Fly   413 ENWFHTGDLGYMDEDGYLFIIDRLKDMLKYQTIMYYPSEIESVIAEMPNVVEACVFGIWDPVYGD 477
            |.|.||||:|....:|.|.|:||.|.:.|.....|...|      ::.||...||..:...|:||
Zfish   550 EGWLHTGDVGQWLPNGTLRIVDRKKHIFKLSQGEYIAPE------KLENVYTRCVPVLQVFVHGD 608

  Fly   478 KAAASVVKKQGTQLEAQDV-VEYVRKR-IPAKFKQL 511
            ...:.::   |..:...:| |.:.::| |...:::|
Zfish   609 SLQSFLI---GIVVPDPEVFVNWAKERGIVGSYEEL 641

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	116/556 (21%)
CG5568	NP_647992.1	Firefly_Luc_like	55..530	CDD:213279	116/556 (21%)
acsl2	XP_002663285.4	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583101
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930