DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5568 and acsm3

DIOPT Version :9

Sequence 1:	NP_647992.1	Gene:	CG5568 / 38658	FlyBaseID:	FBgn0035641	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001104706.1	Gene:	acsm3 / 100002035	ZFINID:	ZDB-GENE-080220-22	Length:	591	Species:	Danio rerio

Alignment Length:	508	Identity:	113/508 - (22%)
Similarity:	195/508 - (38%)	Gaps:	105/508 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 TELTW--KDIQTNAMKVASYMRKL-GLEQGDFVGVIGRLTTHLTALAYACFFNGT---PYHALHT 121
            ||:.|  :::..::.|:|:.:|:: .||:||.|.:|.........:..||...||   |..:..|
Zfish    94 TEVRWSFEELGFHSRKLANVLRQVCSLERGDRVFLILPRVPEWWLVNVACIRTGTVLIPGTSQLT 158

  Fly   122 EYEQSAIERLFGITKPRLIFCDGDEFEKVQAATKGLQVQIVTMRNHPAGILRIQDI-------LT 179
            ..:.          :.|||             |.|.:..|......|     :.|.       ::
Zfish   159 ARDM----------RHRLI-------------TSGAKCVITDETLAP-----LLDTVALDCPSIS 195

  Fly   180 TPVEMNFRPV-----------RLKD-------GTDQLLAILSSSGTSGLPKAVTISNSHQIIGSF 226
            |.:.::.:|:           |:.|       .:::.:.|..:|||:|.||..  .:||...|..
Zfish   196 TKLLLSHKPMDGWGNLTELMGRVSDDHVCVDTSSEEPMTIFFTSGTTGSPKMT--QHSHCSYGLG 258

  Fly   227 LPVDSSI--------IQYNPNTLDWASGITMTI------NAAVFSLTSIIEDCDFDPANLCGLIE 277
            |.|:...        :.:|.:...||.....::      .|.||    :.....||...:...:.
Zfish   259 LTVNGRYWLDLTEQDVFWNTSDTGWAKSAWSSVFAPWIQGACVF----VHHMPRFDTNTVLKTLS 319

  Fly   278 KYRISMVFVSSSQLAMLSNCPEFYAADLSSVKYFFYGGSNC-------SLEVQNKIRSRLSNECV 335
            .|.|:....:.:...||      ...|||  ||.|....:|       :.||..|.: .|:...:
Zfish   320 HYPITTFCTAPTAYRML------VQDDLS--KYKFQALEHCLCAGEPINPEVMCKWK-ELTGLDI 375

  Fly   336 NFSYTLTELNSPGCLNFNFDEKPNSVGRPVRGIQIKIVNELGEAQGPNVVGEICFNNGQKWP--- 397
            ...|..||.............||.|.|:...|..:::|:|.|........|::......:.|
Zfish   376 YEGYGQTETVLIAGTFKGMKIKPGSFGKASPGYDVQVVDENGSVVPKGQEGDLGIRVKPERPFSL 440

  Fly   398 --GYYKNPEETKKMQDSENWFHTGDLGYMDEDGYLFIIDRLKDMLKYQTIMYYPSEIESVIAEMP 460
              .|...|..|.:....: ::.|||.|.||::|||:.|.|..|::........|.|:|:.:.|.|
Zfish   441 FTEYTGEPVRTAECFRGD-FYLTGDRGMMDDEGYLWFIGRSDDVILSAGYRIGPFEVENALIEHP 504

  Fly   461 NVVEACVFGIWDPVYGDKAAASVVKKQGTQLEA-QDVVEYVR---KRIPAKFK 509
            .|.|:.|....|||.|:...|.||.....:..| :::::.::   |.|.|.:|
Zfish   505 AVAESAVVSSPDPVRGEVVKAFVVLTADFKSRAHKELIKELQTHVKSITAPYK 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	113/508 (22%)
CG5568	NP_647992.1	Firefly_Luc_like	55..530	CDD:213279	113/508 (22%)
acsm3	NP_001104706.1	Acs	54..583	CDD:223442	113/508 (22%)
acsm3	NP_001104706.1	AFD_class_I	57..586	CDD:302604	113/508 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010