Protein Alignment vn and Nrg2

DIOPT Version :9

• Sequence 1: NP_523942.2
• Gene: vn / 38657
• FlyBaseID: FBgn0003984
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001129623.2
• Gene: Nrg2 / 432361
• RGDID: 1303302
• Length: 860
• Species: Rattus norvegicus
• Alignment Length: 585
• Identity: 131/585 - (22%)
• Similarity: 189/585 - (32%)
• Gaps: 247/585 - (42%)

  Fly    66 SSYYIPLSSDNGSGSSESSAESGSSSSRSSSNNIDNNILSRLLSLNSNSLSSRSNVKLKPATVFD 130
            |||....||.:.|.::.||:.|..|||||||.:...:..:...|.||.|.|         .::|
  Rat    19 SSYSYSDSSSSSSSNNSSSSTSSRSSSRSSSRSSRGSTTTTSSSENSGSNS---------GSIF- 73

  Fly   131 AGSSTPAQQEQHVAAVPEQQQQQQQQQQSMQKVPNTLINSQIYNLLYNGMPS---------EAAS 186
                       ..||.||.:.|.|.|.:|                     |:         .||:
  Rat    74 -----------RPAAPPEPRPQPQPQPRS---------------------PAARRAAARSRAAAA 106

  Fly   187 SKMRRHIQP--SQLPHQPESRAQLPSNYSSRPAVRSYLIESYEMP---ESMLEDRSPEQAARSRR 246
            ..|||...|  |.|........     ||  |:::|...::|:.|   |..::..:|       .
  Rat   107 GGMRRDPAPGFSMLLFGVSLAC-----YS--PSLKSVQDQAYKAPVVVEGKVQGLAP-------A 157

  Fly   247 DGSNTNGSRQQQRTGHRQQLQQDKRDHRRQRQDQQKEQRQQQQQRQHKSGNKHQQQQQQRRKHQR 311
            .||::|.:|:...:|
  Rat   158 GGSSSNSTREPPASG-------------------------------------------------- 172

  Fly   312 KHQRYNRYCSARDPAQLAFAAPTVFQGVFKSMSADRRVNFSATMKVEKVYKQQHDLQLPTLVRLQ 376
                                                ||   |.:||
  Rat   173 ------------------------------------RV---ALVKV------------------- 179

  Fly   377 FALSNSSGECDIYRERLMPRGMLRSGNDLQQASDIS------------YMMFVQQTNPGNFTILG 429
                             :.:..||||. ||:...||            |:.|::.|.
  Rat   180 -----------------LDKWPLRSGG-LQREQVISVGSCAPLERNQRYIFFLEPTE-------- 218

  Fly   430 QPMRVTHLVVEAVETAVSENYTQ-NAEVTKIF-----SKPSKAIIKH-----GKKLRIVCE-VSG 482
            ||     ||.:.....|..|... ..||.||.     ::|....:|.     |:|..:.|| .:|
  Rat   219 QP-----LVFKTAFAPVDPNGKNIKKEVGKILCTDCATRPKLKKMKSQTGEVGEKQSLKCEAAAG 278

  Fly   483 QPPPKVTWFKDEKSINRKRNI-YQFKHHKRRSELIVRSFN--SSSDAGRYECRAKNKASKAIAKR 544
            .|.|...||||.|.:||.|:| .::.:.::.|.|   .||  ...|||.|.|.|:|...|...:.
  Rat   279 NPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRL---QFNKVKVEDAGEYVCEAENILGKDTVRG 340

  Fly   545 RIMIKASPVHFPTDRSASG--IPCN---FDYCFHNGTCRMIPDINEVYCRCPTEYFGNRCENKWP 604
            |:.:.:...   |..|.||  ..||   ..||.:.|.|..|..||::.|:||..:||.||..|.|
  Rat   341 RLHVNSVST---TLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLSCKCPNGFFGQRCLEKLP 402

  Fly   605  604
              Rat   403  402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vn	NP_523942.2	IGc2	471..538	CDD:197706	27/70 (39%)
		EGF	566..598	CDD:278437	14/34 (41%)
Nrg2	NP_001129623.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..114		36/136 (26%)
		IG	259..344	CDD:214652	30/87 (34%)
		EGF_CA	<369..397	CDD:238011	11/27 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	461..480
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	508..545
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	663..682
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	712..798
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	815..860

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44417
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11100
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2572
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010