DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment vn and stan

DIOPT Version :9

Sequence 1:NP_523942.2 Gene:vn / 38657 FlyBaseID:FBgn0003984 Length:623 Species:Drosophila melanogaster
Sequence 2:NP_001260871.1 Gene:stan / 36125 FlyBaseID:FBgn0024836 Length:3648 Species:Drosophila melanogaster


Alignment Length:317 Identity:77/317 - (24%)
Similarity:115/317 - (36%) Gaps:80/317 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    61 GSAEESSYYIPLSSDNGSGSSESSAESGSSSSRSSSNNIDNNILSRLLSLNSNSLSSRS------ 119
            ||.:..|:| ....|...|.|.|.......|....:..:.:||..:..:|.|..|.::|      
  Fly  3355 GSYKPPSHY-GSEKDYPGGGSGSQTIGHMRSFHPDAAYLSDNIYDKQRTLGSGYLGAKSESPYLS 3418

  Fly   120 ----------------NVKLKPATVFDAGSSTPA--QQEQHVAAVPEQQQQQQQQQQSMQKVPNT 166
                            ::|.:||...|:..|..:  :.:.|       ||||||||..:|...:.
  Fly  3419 KDRITPDIYGSRDGHYSLKRQPAYATDSLHSVHSLLKNDYH-------QQQQQQQQHHLQDRLSE 3476

  Fly   167 LINSQIYNLLYNGMPSEAASSKMRRHIQP-----SQLPHQP-------------ESRAQL--PSN 211
            ..:...|:..|........:.|: .|.||     |||...|             ..|..|  .|.
  Fly  3477 GSDKNGYHFPYTAEEDHLPARKL-SHTQPPSLHGSQLMQPPGVGLVNDVNNPGLMGRHTLNGGSR 3540

  Fly   212 YSSRPAVRSYLIESYEMPESMLEDRSPEQAARS------RRDGSNTNGSRQQQRTGHRQQLQQDK 270
            :|||.:         ..|.:|:....|.....|      ..|...|...|..|     ||.||  
  Fly  3541 HSSRAS---------SPPSTMVAPMQPLGPLTSITDTERNIDDDETTVXRLSQ-----QQQQQ-- 3589

  Fly   271 RDHRRQRQDQQKEQRQQQQQRQHKSGNKHQQQQQQRRKHQRKHQRYNRYCSARDPAQ 327
                 |:|..:.:|||||:|..|:...:|.||.||:|..|:|.::...:.:.|...|
  Fly  3590 -----QQQQLKLQQRQQQKQHPHQQRQQHMQQLQQQRTKQQKQKQTQYFATIRRKPQ 3641

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
vnNP_523942.2 IGc2 471..538 CDD:197706
EGF 566..598 CDD:278437
stanNP_001260871.1 Cadherin_repeat 364..460 CDD:206637
Cadherin_repeat 468..577 CDD:206637
Cadherin_repeat 585..685 CDD:206637
Cadherin_repeat 693..790 CDD:206637
Cadherin_repeat 799..891 CDD:206637
Cadherin_repeat 901..1003 CDD:206637
Cadherin_repeat 1012..1108 CDD:206637
Cadherin_repeat 1118..1216 CDD:206637
Cadherin_repeat 1235..1313 CDD:206637
EGF_CA 1483..1518 CDD:238011
LamG 1558..1734 CDD:238058
EGF 1760..1789 CDD:278437
Laminin_G_2 1826..1944 CDD:280389
TNFRSF <1963..2061 CDD:304602
EGF_Lam 2095..2140 CDD:214543
HRM 2144..2200 CDD:280888
GAIN 2293..2458 CDD:293098
GPS 2743..2802 CDD:295363
7tm_4 2809..3028 CDD:304433
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.910

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