DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment vn and Nrg1

DIOPT Version :9

Sequence 1:NP_523942.2 Gene:vn / 38657 FlyBaseID:FBgn0003984 Length:623 Species:Drosophila melanogaster
Sequence 2:XP_038950018.1 Gene:Nrg1 / 112400 RGDID:621341 Length:850 Species:Rattus norvegicus


Alignment Length:245 Identity:54/245 - (22%)
Similarity:87/245 - (35%) Gaps:55/245 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   410 DISYMMFVQ-QTN-----PGNFTILGQPMRVTHLVVEAVETAVSENYTQNAEVTKIFSKPSKAII 468
            |..|:.|:: ..|     |..|.....|:.....:.:.|...:.:.......:.::.|:.|.|  
  Rat   198 DSRYIFFMEPDANSSGRAPPAFRASFPPLETGRNLKKEVSRVLCKRCALPPRLKEMKSQESAA-- 260

  Fly   469 KHGKKLRIVCEVSGQ-PPPKVTWFKDEKSINRKRNIYQFKHHKR--RSELIVRSFNSSSDAGRYE 530
              |.||.:.||.|.: ...:..|||:...:|||......|..|:  :|||.:.. .|.:|:|.|.
  Rat   261 --GSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPENIKIQKKPGKSELRINK-ASLADSGEYM 322

  Fly   531 CRAKNKASKAIAKRRIMI--------------------KASPVHF-----------PTDRSASG- 563
            |:..:|.....|...|.|                    ..||:..           .|..|.:| 
  Rat   323 CKVISKLGNDSASANITIVESNEFITGMPASTETAYVSSESPIRISVSTEGANTSSSTSTSTTGT 387

  Fly   564 ---IPC---NFDYCFHNGTCRMIPDI---NEVYCRCPTEYFGNRCENKWP 604
               |.|   ...:|.:.|.|..:.|:   :...|:|...:.|.||....|
  Rat   388 SHLIKCAEKEKTFCVNGGECFTVKDLSNPSRYLCKCQPGFTGARCTENVP 437

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
vnNP_523942.2 IGc2 471..538 CDD:197706 23/69 (33%)
EGF 566..598 CDD:278437 8/37 (22%)
Nrg1XP_038950018.1 Ig_Pro_neuregulin-1 248..340 CDD:409476 28/96 (29%)
Ig strand B 264..268 CDD:409476 1/3 (33%)
Ig strand C 278..282 CDD:409476 0/3 (0%)
Ig strand E 306..310 CDD:409476 3/3 (100%)
Ig strand F 320..325 CDD:409476 2/4 (50%)
Ig strand G 333..336 CDD:409476 1/2 (50%)
EGF_CA <401..433 CDD:238011 8/31 (26%)
Neuregulin 478..832 CDD:396641
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_28J9V
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm44417
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X2572
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.810

Return to query results.
Submit another query.