DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kri and Uckl1

DIOPT Version :9

Sequence 1:	NP_001261451.1	Gene:	kri / 38655	FlyBaseID:	FBgn0035639	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001365934.1	Gene:	Uckl1 / 68556	MGIID:	1915806	Length:	549	Species:	Mus musculus

Alignment Length:	247	Identity:	90/247 - (36%)
Similarity:	131/247 - (53%)	Gaps:	20/247 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 HQQPQQEAQEQEQQLHTPTHAHAAVPAATSEEILAEYGSNLKLLECNSQVAELLTILRDKNTTRS 86
            |...|.|.::....:.....||...|..          ..|.:|:...||..:.||:|||.|:|.
Mouse   295 HVHSQLEERKLRWDMAALASAHQCHPLP----------QTLSVLKSTPQVRGMHTIIRDKETSRD 349

  Fly    87 DFKFYADRLIRLVIEESLNQLPYTHCDVETPTGAIYEGLKYRSGN-CGVSIIRSGEAMEQGLRDC 150
            :|.||:.||:||:||.:|:.||:..|.|:||.|..|.|..|.... .||||:|:||.||..||..
Mouse   350 EFIFYSKRLMRLLIEHALSFLPFQDCTVQTPQGQDYVGKCYAGKQITGVSILRAGETMEPALRAV 414

  Fly   151 CRSIRIGKILVESDANTHEARVVYARFPDDIGSRQVLLMYPIMSTGNTVLQAVNVLREHGVPESC 215
            |:.:|||.||::::..|.|..:.|.|.|.||....|:||...:|||...:.||.||.:|.|||..
Mouse   415 CKDVRIGTILIQTNQLTGEPELHYLRLPKDISDDHVILMDCTVSTGAAAMMAVRVLLDHDVPEDK 479

  Fly   216 IILSNLFCTPIAARTVVNAFPKLKILT-------SELHPVAP--NHFGQKYF 258
            |.|.:|....:...:|..|||:::|:|       ::|..:.|  .:||.:||
Mouse   480 IFLLSLLMAEMGVHSVAYAFPRVRIITTAVDKRVNDLFRIIPGIGNFGDRYF 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kri	NP_001261451.1	UPRTase	70..245	CDD:291353	76/182 (42%)
Uckl1	NP_001365934.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..74
		UMPK	101..299	CDD:238981	1/3 (33%)
		UPRTase	330..533	CDD:405383	82/202 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D929897at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	1	1.100	-	-	O	PTHR10285
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1606
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950