DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kri and uprt

DIOPT Version :9

Sequence 1:	NP_001261451.1	Gene:	kri / 38655	FlyBaseID:	FBgn0035639	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_996974.1	Gene:	uprt / 404623	ZFINID:	ZDB-GENE-040426-2411	Length:	257	Species:	Danio rerio

Alignment Length:	242	Identity:	142/242 - (58%)
Similarity:	175/242 - (72%)	Gaps:	14/242 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SSSSDHQQPQQEAQEQEQQLHTPTHAHAAVPAATSEEILAEYGSNLKLLECNSQVAELLTILRDK 81
            ||::..:..|.:|::.|.|              |:.||..:.|..||||..|.|:.||.||:|||
Zfish    27 SSAAAAETCQNDAEQPEYQ--------------TTSEIHQQIGPQLKLLPLNDQIRELQTIIRDK 77

  Fly    82 NTTRSDFKFYADRLIRLVIEESLNQLPYTHCDVETPTGAIYEGLKYRSGNCGVSIIRSGEAMEQG 146
            .|:|.||.|.||||||||:||.||||||:.|.|.||||..|||:|:..|||||||:|||||||||
Zfish    78 TTSRGDFVFCADRLIRLVVEEGLNQLPYSECTVTTPTGHKYEGVKFEKGNCGVSIMRSGEAMEQG 142

  Fly   147 LRDCCRSIRIGKILVESDANTHEARVVYARFPDDIGSRQVLLMYPIMSTGNTVLQAVNVLREHGV 211
            ||||||||||||||::||..|.:|:|.||:||.||..|:|||||||:||||||::||.||.|||:
Zfish   143 LRDCCRSIRIGKILIQSDEETQKAKVYYAKFPPDISRRKVLLMYPILSTGNTVIEAVRVLTEHGL 207

  Fly   212 PESCIILSNLFCTPIAARTVVNAFPKLKILTSELHPVAPNHFGQKYF 258
            ....|||.:||.||..||::|..||.:.|||:|:|.|||.||||:||
Zfish   208 QAKHIILLSLFSTPHGARSIVQEFPDITILTTEVHAVAPTHFGQRYF 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kri	NP_001261451.1	UPRTase	70..245	CDD:291353	116/174 (67%)
uprt	NP_996974.1	UPRTase	66..256	CDD:291353	127/189 (67%)
		5-phospho-alpha-D-ribose 1-diphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q26998	186..194		6/7 (86%)
		Uracil binding. /evidence=ECO:0000250\|UniProtKB:Q26998	247..249		0/1 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579256
Domainoid	1	1.000	240	1.000	Domainoid score	I2220
eggNOG	1	0.900	-	-		E1_COG0035
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H25175
Inparanoid	1	1.050	280	1.000	Inparanoid score	I2880
OMA	1	1.010	-	-		QHG53753
OrthoDB	1	1.010	-	-		D488474at33208
OrthoFinder	1	1.000	-	-		FOG0005529
OrthoInspector	1	1.000	-	-		oto39581
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1606
SonicParanoid	1	1.000	-	-		X4480
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.740