DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kri and C47B2.2

DIOPT Version :9

Sequence 1:	NP_001261451.1	Gene:	kri / 38655	FlyBaseID:	FBgn0035639	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001252032.1	Gene:	C47B2.2 / 3565732	WormBaseID:	WBGene00008131	Length:	231	Species:	Caenorhabditis elegans

Alignment Length:	224	Identity:	105/224 - (46%)
Similarity:	141/224 - (62%)	Gaps:	13/224 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 VPAATSEE--------ILAEYGSNLKLLECNSQVAELLTILRDKNTTRSDFKFYADRLIRLVIEE 102
            :|....||        .|.|.|:|..||:...|:.||.|||:|::|..|||.|.||||:||||||
Worm    13 IPKVGDEEDGVGQLVANLKEKGTNFVLLKKTPQILELQTILKDRSTNHSDFVFNADRLMRLVIEE 77

  Fly   103 SLNQLPYTHCDVETPTGAIYEGLKYRSGNCGVSIIRSGEAMEQGLRDCCRSIRIGKILVESDANT 167
            .||.||:|...|.||||..|||:::..||||||:.|||||||..||.|||.|||||||:..
Worm    78 CLNHLPFTEHTVTTPTGFKYEGIQFNRGNCGVSLCRSGEAMEVSLRQCCRCIRIGKILIGD---- 138

  Fly   168 HEARVVYARFPDDIGSRQVLLMYPIMSTGNTVLQAVNVLREHGVPESCIILSNLFCTPIAARTVV 232
             |.:|:|||...||.||:|||:||.:.:|.||.:|:.||:|..||:..|.|.:||.:|...:.:.
Worm   139 -EQKVLYARLLPDITSRRVLLLYPTIGSGTTVCKAIEVLKEARVPDENIYLVSLFISPTGLKNIT 202

  Fly   233 NAFPKLKILTSELHPVAPNHFGQKYFDCI 261
            ..:|.:.::.|::..:.||||...||..:
Worm   203 RKYPYITVVASDITSLYPNHFSTSYFGAV 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kri	NP_001261451.1	UPRTase	70..245	CDD:291353	90/174 (52%)
C47B2.2	NP_001252032.1	UPRTase	43..215	CDD:291353	90/176 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158691
Domainoid	1	1.000	178	1.000	Domainoid score	I2138
eggNOG	1	0.900	-	-		E1_COG0035
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H25175
Inparanoid	1	1.050	201	1.000	Inparanoid score	I2468
Isobase	1	0.950	-	0	Normalized mean entropy	S942
OMA	1	1.010	-	-		QHG53753
OrthoDB	1	1.010	-	-		D488474at33208
OrthoFinder	1	1.000	-	-		FOG0005529
OrthoInspector	1	1.000	-	-		oto19336
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1606
SonicParanoid	1	1.000	-	-		X4480
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.690