DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kri and SPCC162.11c

DIOPT Version :9

Sequence 1:	NP_001261451.1	Gene:	kri / 38655	FlyBaseID:	FBgn0035639	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001342737.1	Gene:	SPCC162.11c / 2538946	PomBaseID:	SPCC162.11c	Length:	454	Species:	Schizosaccharomyces pombe

Alignment Length:	235	Identity:	70/235 - (29%)
Similarity:	114/235 - (48%)	Gaps:	26/235 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 QQLHTPTHAHAAVPAATSEEILAEYGSNLKLLECNSQVAELLTILRDKNTTRSDFKFYADRLIRL 98
            ||: .||..|..:              ||..|:...:::.:.|||.:|||...|.:|:..|:..:
pombe   238 QQI-VPTIPHLPL--------------NLVQLKITPEISAIRTILINKNTHPDDLQFFLSRIGTM 287

  Fly    99 VIEESLNQLPYTHCDVETPTGAIYEGLKYRSGNCGVSIIRSGEAMEQGLRDCCR---SIRIGKIL 160
            ::..:.:.|.|....:....|..:|||:.....||||::|||..:|..|   ||   ::.:||||
pombe   288 LMNLAGDSLAYEKKTITLHNGNQWEGLQMAKELCGVSVLRSGGTLETAL---CRQFPTVCLGKIL 349

  Fly   161 VESDANTHEARVVYARFPDDIGSRQVLLMYPIMSTGNTVLQAVNVLREHGVPESCIILSNLFCTP 225
            |:.:..|.|..:.|.:.|..|.:..|:||...::|...||.|..:|.:.||||..||:....|..
pombe   350 VQINKVTQEPTLHYHKLPRGIATMNVVLMASHLTTHADVLMATQILVDFGVPEENIIIVVYVCYS 414

  Fly   226 IAARTVVNAFPKLKILTSELHPVAPNHFG-----QKYFDC 260
            .:.:.:...|||:.|:|:.|..||....|     :.|:.|
pombe   415 ESIKALAYIFPKVTIVTAFLESVAEPVVGRLDIEKVYYGC 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kri	NP_001261451.1	UPRTase	70..245	CDD:291353	56/177 (32%)
SPCC162.11c	NP_001342737.1	UMPK	23..220	CDD:238981
SPCC162.11c	NP_001342737.1	Upp	250..454	CDD:223113	64/206 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	1	1.100	-	-	O	PTHR10285
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1606
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940