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Protein Alignment S6k and RPS6KA5

DIOPT Version :9

Sequence 1:	NP_001261450.1	Gene:	S6k / 38654	FlyBaseID:	FBgn0283472	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_004746.2	Gene:	RPS6KA5 / 9252	HGNCID:	10434	Length:	802	Species:	Homo sapiens

Alignment Length:	364	Identity:	184/364 - (50%)
Similarity:	245/364 - (67%)	Gaps:	14/364 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 GQETIQLCEE----NVNPGKIKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKA 114
            |::.:.:..|    |:.....|:|.::|||.||||.|.|||||.|||.:|.|..|.:||||||||
Human    22 GEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKA 86

  Fly   115 SIVTNQKDTAHTRAERNILEAVKH-PFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLE 178
            :||...|.|.|||.||.:||.::. ||:|.|.|||||:.||:|||:|::|||||.||.:...|.|
Human    87 TIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTE 151

  Fly   179 DTTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHI-QEGIVTHTFCGT 242
            .....|:.||:|||.|||||||||||:|.||||||:.|||.||||||.||.: .|....::||||
Human   152 HEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGT 216

  Fly   243 IEYMAPEILT--RSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKT----IETILKAKLNLPAY 301
            ||||||:|:.  .|||.|||||||||.||:::|||..|||.:..|.:    ...|||::...|..
Human   217 IEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQE 281

  Fly   302 LTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVS 366
            ::..|:||::||:.:...:|||.||.||..::.|.||:.:||||:.|:::..|.||::|.|.|||
Human   282 MSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVS 346

  Fly   367 QFDTRFTRQIPVDSPDDTTLSESANLIFQGFTYVAPSIL 405
            .|...||...|..||  ..|.:|:..:|||:::||||||
Human   347 NFAEEFTEMDPTYSP--AALPQSSEKLFQGYSFVAPSIL 383

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.