Sequence 1: | NP_001261450.1 | Gene: | S6k / 38654 | FlyBaseID: | FBgn0283472 | Length: | 490 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_003933.1 | Gene: | RPS6KA4 / 8986 | HGNCID: | 10433 | Length: | 772 | Species: | Homo sapiens |
Alignment Length: | 427 | Identity: | 198/427 - (46%) |
---|---|---|---|
Similarity: | 261/427 - (61%) | Gaps: | 39/427 - (9%) |
- Green bases have known domain annotations that are detailed below.
Fly 27 DSDDDRIELDDVDLEPELCINLHQDTEGQETIQLCEENVNPGKIKLGPKDFELKKVLGKGGYGKV 91
Fly 92 FQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAERNILEAVKH-PFIVELVYAFQTDGKLY 155
Fly 156 LILEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKL 220
Fly 221 TDFGLCKEHI-QEGIVTHTFCGTIEYMAPEIL-TRSGHGKAVDWWSLGALMFDMLTGVPPFTAEN 283
Fly 284 RKKT----IETILKAKLNLPAYLTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWD 344
Fly 345 DVLARRLEPPIKPLLRSEDDVSQFDTRFTRQIPVDSPDDTTLSESANLIFQGFTYVAPSILEDMH 409
Fly 410 R-----------ANRMPARSPRRTPRQLPDSSFRLQF 435 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
S6k | NP_001261450.1 | PTZ00263 | 76..397 | CDD:140289 | 174/327 (53%) |
STKc_p70S6K | 81..402 | CDD:270736 | 173/327 (53%) | ||
RPS6KA4 | NP_003933.1 | STKc_MSK2_N | 32..364 | CDD:270765 | 176/332 (53%) |
S_TKc | 33..301 | CDD:214567 | 151/267 (57%) | ||
PKc_like | 404..714 | CDD:304357 | 2/5 (40%) | ||
S_TKc | 417..674 | CDD:214567 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 673..696 | ||||
Required for nuclear targeting and association with MAPK14 | 725..772 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 728..772 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165140571 | |
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D1132245at2759 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R469 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.880 |