Protein Alignment S6k and SCH9

DIOPT Version :10

• Sequence 1: NP_523941.2
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_012075.1
• Gene: SCH9 / 856612
• SGDID: S000001248
• Length: 824
• Species: Saccharomyces cerevisiae
• Alignment Length: 442
• Identity: 176/442 - (39%)
• Similarity: 253/442 - (57%)
• Gaps: 42/442 - (9%)

  Fly     3 DVSDP----SELFDLELHDLELQDDKARDSDDDRIELDDVDLEPELCINLHQDTEGQETI--QLC 61
            |.|.|    ...||:.....|| |....|:..|.:.|..|.|.|.:....|.......::  ::.
Yeast   322 DSSHPIWHHKTTFDVLGSHSEL-DISVYDAAHDHMFLGQVRLYPMIHNLAHASQHQWHSLKPRVI 385

  Fly    62 EENVNPGKIKL------------GPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKA 114
            :|.|: |.|.:            ||:|||:.::||||.:|:|:||:|   :|..:.:|||||.|
Yeast   386 DEVVS-GDILIKWTYKQTKKRHYGPQDFEVLRLLGKGTFGQVYQVKK---KDTQRIYAMKVLSK- 445

  Fly   115 SIVTNQKDTAHTRAERNIL---EAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIF 176
            .::..:.:.|||..|||||   .:...||||.|.::|||...|||:.:|:||||||.||::||.|
Yeast   446 KVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRF 510

  Fly   177 LEDTTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCG 241
            .||...||::|::|||.|||...|:|||||||||||||.|::.|.||||.|..:::.  |:||||
Yeast   511 SEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNTFCG 573

  Fly   242 TIEYMAPE-ILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPA-YLTP 304
            |.||:||| :|..:|:.|.||:||||.|:|:|..|..||.|||.:|..:.|...|:..|. .|:.
Yeast   574 TTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQ 638

  Fly   305 EARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFD 369
            |.|..|:.|:.|....|||: .:|...::.||||..::|:.:..:::.||.||.|.||.|.|.||
Yeast   639 EGRSFVKGLLNRNPKHRLGA-IDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFD 702

  Fly   370 TRFT--------RQIPVDSPDDTTLSESANLIFQGFTYVAPSILEDMHRANR 413
            ..||        :..|:.:.  |.||.:....|.|||:|..|.:::....||
Yeast   703 PEFTTASTSYMNKHQPMMTA--TPLSPAMQAKFAGFTFVDESAIDEHVNNNR 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_523941.2	STKc_p70S6K	81..402	CDD:270736	149/333 (45%)
SCH9	NP_012075.1	YPK1_N_like	181..407	CDD:212165	19/86 (22%)
		STKc_Sck1_like	418..738	CDD:270738	147/328 (45%)