Protein Alignment S6k and YPK2

DIOPT Version :10

• Sequence 1: NP_523941.2
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_013822.1
• Gene: YPK2 / 855130
• SGDID: S000004710
• Length: 677
• Species: Saccharomyces cerevisiae
• Alignment Length: 423
• Identity: 178/423 - (42%)
• Similarity: 251/423 - (59%)
• Gaps: 37/423 - (8%)

  Fly     7 PSELFDLELHDLELQDDKARD-----SDDDRIELDDVDLEPELCINLHQDTEGQETIQLCEE--- 63
            ||:.:..|:.:   ||:..::     :.:..|.||...|.    :||..|:..|  |:|...
Yeast   261 PSKNWQQEIGE---QDEVLKEILKKINTNQDIHLDSFHLP----LNLKIDSAAQ--IRLYNHHWI 316

  Fly    64 -------------NVNPGKIK-LGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKA 114
                         :..|.|.| |...||:|.||:|||.:|||.||||   :|..|.:|:|.|:||
Yeast   317 SLERGYGKLNITVDYKPSKNKPLSIDDFDLLKVIGKGSFGKVMQVRK---KDTQKIYALKALRKA 378

  Fly   115 SIVTNQKDTAHTRAERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLED 179
            .|| ::.:..||.|||.:|..|..||||.|.::||:..||||:|.:::|||||.||:.||.|...
Yeast   379 YIV-SKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLA 442

  Fly   180 TTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTIE 244
            .:.||::|::.||..||||.:|||||||||||||.|||:.|.||||||.::::...|.|||||.|
Yeast   443 RSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPE 507

  Fly   245 YMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTPEARDL 309
            |:|||||...|:.|.||||:||.|:::|:||:||:..||.....:.||:..|..|....|.|:||
Yeast   508 YLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDL 572

  Fly   310 VRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTR 374
            :..|:.|...:|||....|  .::.|||||.::|..:|.:...||.||:::||.|.:.||..||:
Yeast   573 LIGLLSRDPSRRLGVNGTD--EIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTK 635

  Fly   375 QIPVDSPDDTTLSESANLIFQGFTYVAPSILED 407
            :.|:||..|..||.|....|.|:||:....|.|
Yeast   636 EKPIDSVVDEYLSASIQKQFGGWTYIGDEQLGD 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_523941.2	STKc_p70S6K	81..402	CDD:270736	154/320 (48%)
YPK2	NP_013822.1	YPK1_N_like	114..339	CDD:212165	18/86 (21%)
		Protein Kinases, catalytic domain	349..660	CDD:473864	151/316 (48%)