Protein Alignment S6k and DBF2

DIOPT Version :10

• Sequence 1: NP_523941.2
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_011606.3
• Gene: DBF2 / 852984
• SGDID: S000003324
• Length: 572
• Species: Saccharomyces cerevisiae
• Alignment Length: 469
• Identity: 130/469 - (27%)
• Similarity: 209/469 - (44%)
• Gaps: 118/469 - (25%)

  Fly    18 LELQDDKARDSDDDRIELDDVDLEPELCINLHQDTEGQETIQLCEENVNPGKIKLGPKDFELKKV 82
            ||....:::..:.|:|:|::               |....:|...:.:...::|...:|||:...
Yeast   133 LEYLQQQSQLPNSDQIKLNE---------------EWSSYLQREHQVLRKRRLKPKNRDFEMITQ 182

  Fly    83 LGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAERNILEAVKHPFIVELVYA 147
            :|:||||:|:..||   :|..:..|:|:|.| .::....:|.|...||:||...:..::|:|:||
Yeast   183 VGQGGYGQVYLARK---KDTKEVCALKILNK-KLLFKLNETKHVLTERDILTTTRSEWLVKLLYA 243

  Fly   148 FQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTC-------FYLSEIILALGHLHKLGIIYRDL 205
            ||....|||.:|::.||: |..|      |.:|.|       ||:||:..|:..||.||..:|||
Yeast   244 FQDLQSLYLAMEFVPGGD-FRTL------LINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDL 301

  Fly   206 KPENILLDAQGHVKLTDFGLC-----KEHIQ---------------------------------- 231
            ||||.|:||:||:|||||||.     .|.|:
Yeast   302 KPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLRE 366

  Fly   232 -EGIVTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAK 295
             |....::..|:.:|||.|:|....:...||:||||.::|:.|.|..||:..:..:|.:.:.:.|
Yeast   367 KEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWK 431

  Fly   296 LNL--------PAYLTPEARDLVRRLMKRQEP-QRLGSGPEDAAAVQIHPFFKHVNWDDVLARRL 351
            ..|        .|..:....||:.||:  .:| .||.|...    |:...:|..:|:..:  |.:
Yeast   432 QTLRRPRQSDGRAAFSDRTWDLITRLI--ADPINRLRSFEH----VKRMSYFADINFSTL--RSM 488

  Fly   352 EPPIKPLLRSEDDVSQFD------------TRFTRQIPVDS-PDDTTLSE--------------- 388
            .||..|.|.||.|...||            ..|.||..:.: .||:.:|.
Yeast   489 IPPFTPQLDSETDAGYFDDFTSEADMAKYADVFKRQDKLTAMVDDSAVSSKLVGFTFRHRNGKQG 553

  Fly   389 SANLIFQGFTYVAP 402
            |:.::|.|..:..|
Yeast   554 SSGILFNGLEHSDP 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_523941.2	STKc_p70S6K	81..402	CDD:270736	118/404 (29%)
DBF2	NP_011606.3	MobB_Sid2p-like	85..172	CDD:439271	7/53 (13%)
		STKc_Sid2p_like	165..547	CDD:270751	119/400 (30%)