Protein Alignment S6k and sgk1

DIOPT Version :10

• Sequence 1: NP_523941.2
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: XP_012818527.1
• Gene: sgk1 / 594981
• XenbaseID: XB-GENE-1003518
• Length: 434
• Species: Xenopus tropicalis
• Alignment Length: 366
• Identity: 160/366 - (43%)
• Similarity: 229/366 - (62%)
• Gaps: 28/366 - (7%)

  Fly    59 QLCEENVNP-----GKIKLG--------PKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKV 110
            :|..||.:|     .:|.||        |.||:..|::|||.:|||...|..|.   .|::|:||
 Frog    70 ELLNENSSPPPSPSQQINLGPSSNPHAKPSDFQFLKIIGKGSFGKVLLARHNAD---EKFYAVKV 131

  Fly   111 LKKASIVTNQKDTAHTRAERNI-LEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREG 174
            |:|.:|: .:|:..|..:|||: |:.|||||:|.|.::|||..:||.||:|::|||||.||:||.
 Frog   132 LQKKAIL-KKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTTSRLYFILDYINGGELFYHLQRER 195

  Fly   175 IFLEDTTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTF 239
            .|||....||.:||..|||:||.|.|:||||||||||||:|||:.|||||||||:|:....|.||
 Frog   196 CFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTF 260

  Fly   240 CGTIEYMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTP 304
            |||.||:|||:|.:..:.:.||||.|||::::||.|:|||.:.|..:..:.||...|.|...:|.
 Frog   261 CGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITN 325

  Fly   305 EARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFD 369
            .||:|:..|:::...:|:|: ..|...::.|.||..:||||::.:::.||..|.:....|:..||
 Frog   326 SARNLLEGLLQKDRTKRIGA-KNDFMEIKNHMFFSPINWDDLINKKITPPFNPNVSGPSDLQHFD 389

  Fly   370 TRFTRQIPV-----DSPDDTTLSES---ANLIFQGFTYVAP 402
            ..||.: ||     .|||...::.|   |...|.||:|..|
 Frog   390 PEFTEE-PVPNSIGQSPDSILITASIKEAAEAFMGFSYAPP 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_523941.2	STKc_p70S6K	81..402	CDD:270736	149/329 (45%)
sgk1	XP_012818527.1	STKc_SGK1	93..431	CDD:270753	153/343 (45%)