Protein Alignment S6k and Rps6ka3

DIOPT Version :10

• Sequence 1: NP_523941.2
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: XP_017457618.1
• Gene: Rps6ka3 / 501560
• RGDID: 1563860
• Length: 759
• Species: Rattus norvegicus
• Alignment Length: 434
• Identity: 190/434 - (43%)
• Similarity: 267/434 - (61%)
• Gaps: 44/434 - (10%)

  Fly    18 LELQDDKARDSDDDRIEL------DDVDLEPELCINLHQDTEGQETIQ--LCEENVNP------- 67
            :.::..::..||..:.::      :::.|.|...::......||:.:.  :.||.:||
  Rat     2 ISVEPSQSAVSDSTKKKILWPRINEELILNPVTLVHRFFLQNGQQIMDEPMGEEEINPQTEEGSI 66

  Fly    68 -----------GKIKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQK 121
                       |..|..|..|||.||||:|.:||||.|:|.:|.||.:.:||||||||::  ..:
  Rat    67 KEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL--KVR 129

  Fly   122 DTAHTRAERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLS 186
            |...|:.||:||..|.|||||:|.|||||:|||||||::|.||:||..|.:|.:|.|:...|||:
  Rat   130 DRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLA 194

  Fly   187 EIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTIEYMAPEIL 251
            |:.|||.|||.||||||||||||||||.:||:|||||||.||.|......::||||:||||||::
  Rat   195 ELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV 259

  Fly   252 TRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTPEARDLVRRLMKR 316
            .|.||.::.||||.|.|||:||||..||..::||:|:..||||||.:|.:|:|||:.|:|.|.||
  Rat   260 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKR 324

  Fly   317 QEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTRQIPVDSP 381
            ....|||:||:....::.|.||..::|:.:..|.:.||.||.....:|...||..||.:.|.|||
  Rat   325 NPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSP 389

  Fly   382 DDTTLSESANLIFQGFTYVA---------------PSILEDMHR 410
             ....|.:|:.:|:||::||               .||::.:||
  Rat   390 -GIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQQLHR 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_523941.2	STKc_p70S6K	81..402	CDD:270736	170/335 (51%)
Rps6ka3	XP_017457618.1	STKc_RSK_N	91..407	CDD:270734	168/318 (53%)
		STKc_RSK2_C	421..759	CDD:271078	4/12 (33%)