Protein Alignment S6k and rps6kb1b

DIOPT Version :10

• Sequence 1: NP_523941.2
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_998241.1
• Gene: rps6kb1b / 406349
• ZFINID: ZDB-GENE-040426-2038
• Length: 502
• Species: Danio rerio
• Alignment Length: 511
• Identity: 302/511 - (59%)
• Similarity: 354/511 - (69%)
• Gaps: 53/511 - (10%)

  Fly    10 LFDLELHDLELQDDKARDSDDDRIELDDVDLEPELCINLHQDTEGQETIQLCEENVNPGKIKLGP 74
            :||::|      |....:..||.:|...::...:.|.....:.:..|.|::.|:|||.|...:.|
Zfish     4 VFDIDL------DQPEENVSDDELEEAQINELMDQCSGFEFNMDDCEKIEISEDNVNQGTENIRP 62

  Fly    75 KDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAERNILEAVKHP 139
            :.|||.:|||||||||||||||.:|....|.|||||||||.||.|.||||||:|||||||.||||
Zfish    63 ECFELLRVLGKGGYGKVFQVRKVSGAATGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHP 127

  Fly   140 FIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALGHLHKLGIIYRD 204
            |||:|:|||||.|||||||||||||||||.|||||||:|||.||||:||.:||||||:.||||||
Zfish   128 FIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRD 192

  Fly   205 LKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALM 269
            ||||||:|:.||||||||||||||.|.:|.|||||||||||||||||.||||.:|||||||||||
Zfish   193 LKPENIMLNNQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALM 257

  Fly   270 FDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQI 334
            :|||||.||||.|||||||:.|||.|||||.|||.|||||::||:||....|||:||.||..||.
Zfish   258 YDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKRLLKRSASSRLGAGPGDATEVQT 322

  Fly   335 HPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTRQIPVDSPDDTTLSESANLIFQGFTY 399
            ||||:||||||:|||::|||.||.|:..:||||||::||.|.|||||||:|||||||.:|.||||
Zfish   323 HPFFRHVNWDDLLARKVEPPFKPFLQFAEDVSQFDSKFTSQTPVDSPDDSTLSESANQVFLGFTY 387

  Fly   400 VAPSILEDMHR--ANRMPARSPRR---TPR-----------------QLPDSSFRLQFPSANVGA 442
            ||||:||::..  :.....|||||   :||                 .||.|| .||.|:
Zfish   388 VAPSVLENIKEKFSFEPKIRSPRRFLGSPRTPLSPIKFSGDCWPRGPTLPGSS-TLQSPT----- 446

  Fly   443 NAPLAM------HGHSQRSGMFARATPPHHMQTFAPRPSPAQDEM--MDVQGLPMV 490
              .|||      |...|.|   |.||.|      .|...||...|  ...|..|::
Zfish   447 --ELAMEVSSVDHMDVQAS---AEATAP------LPIRQPAGSNMGQFKQQAYPVI 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_523941.2	STKc_p70S6K	81..402	CDD:270736	248/320 (78%)
rps6kb1b	NP_998241.1	STKc_p70S6K	68..390	CDD:270736	248/321 (77%)