Protein Alignment S6k and Gprk1

DIOPT Version :10

• Sequence 1: NP_523941.2
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001036438.1
• Gene: Gprk1 / 3355013
• FlyBaseID: FBgn0260798
• Length: 700
• Species: Drosophila melanogaster
• Alignment Length: 276
• Identity: 53/276 - (19%)
• Similarity: 93/276 - (33%)
• Gaps: 104/276 - (37%)

  Fly    57 ERPNASNF--SWN-----YAIFWQISRSKAGDLVLCWGDGYCREPKEGEKSEIVRILSMGREEE- 113
            :||....:  :|.     .:::.:|..|:..|:          |.||    |.:|.|.|.|..:
  Fly    17 KRPENQTYISAWRDRSEFQSVYEKIFNSRPDDI----------ETKE----EALRWLKMWRTRQM 67

  Fly   114 ---------THQTMRKRVLQKLHDLFGGSEEENCALGLDRVTDTEMFLLSSMYFSFPRGEGGPGK 169
                     |.|.:..:|.. |......|:|...|:.:..:.....    :.:.:|....||..|
  Fly    68 KEVPICVRCTFQILEAQVFD-LRSQRAASDEVGNAMEIKNIYAGAF----TRFINFLTEGGGTRK 127

  Fly   170 ----------------------CFASAKPVWLS-DVVNSGSDYCV----RSFLAKS-AGIQTVVL 206
                                  |  :.:.|.:| ||....:.||:    |::..:. :|:|.|.|
  Fly   128 KSIADSVREIGIETYLVELRHLC--AHRSVSISIDVFRRSAQYCMDWLKRAYWQRELSGMQPVSL 190

  Fly   207 VPT------------DLGVV------------------ELGSTSC-LPESEDSILSIRSLFTSSL 240
             ||            |:.|:                  |:...|. |.|:|..:|.:.:
  Fly   191 -PTLKYYYVAEDQLPDMSVILRTYDAVTAARVRRAYTLEMAIESVGLAEAETKLLEVHA------ 248

  Fly   241 PPVRAVALPVTVAEKI 256
            ...|:|.|||.|.:.:
  Fly   249 QEHRSVRLPVIVRQTV 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_523941.2	STKc_p70S6K	81..402	CDD:270736	48/245 (20%)
Gprk1	NP_001036438.1	RGS_GRK2_GRK3	30..186	CDD:188701	31/176 (18%)
		Protein Kinases, catalytic domain	185..531	CDD:473864	19/87 (22%)
		PH_GRK2_subgroup	552..675	CDD:269946