DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment S6k and Rps6ka5

DIOPT Version :9

Sequence 1:	NP_001261450.1	Gene:	S6k / 38654	FlyBaseID:	FBgn0283472	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_001382521.1	Gene:	Rps6ka5 / 314384	RGDID:	1308336	Length:	798	Species:	Rattus norvegicus

Alignment Length:	364	Identity:	185/364 - (50%)
Similarity:	246/364 - (67%)	Gaps:	14/364 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 GQETIQLCEE----NVNPGKIKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKA 114
            |::.:.:..|    |:.....|:|.::|||.||||.|.|||||.|||.:|.||.|.:||||||||
  Rat    21 GEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDAGKLYAMKVLKKA 85

  Fly   115 SIVTNQKDTAHTRAERNILEAVKH-PFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLE 178
            :||...|.|.|||.||.:||.::. ||:|.|.|||||:.||:|||:|::|||||.||.:...|.|
  Rat    86 TIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTE 150

  Fly   179 DTTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHI-QEGIVTHTFCGT 242
            .....|:.||:|||.|||||||||||:|.||||||:.|||.||||||.||.: .|....::||||
  Rat   151 HEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADEAERAYSFCGT 215

  Fly   243 IEYMAPEILT--RSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKT----IETILKAKLNLPAY 301
            ||||||:|:.  .|||.|||||||||.||:::|||..|||.:..|.:    ...|||::...|..
  Rat   216 IEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQG 280

  Fly   302 LTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVS 366
            ::..|:||::||:.:...:|||.||.||..::.|.||:.:||||:.|:::..|.||::|.|.|||
  Rat   281 MSSVAKDLLQRLLMKDPKKRLGCGPRDAEEIKEHLFFEKINWDDLAAKKVPAPFKPVIRDELDVS 345

  Fly   367 QFDTRFTRQIPVDSPDDTTLSESANLIFQGFTYVAPSIL 405
            .|...||...|..||  ..|.:|:..:|||:::||||||
  Rat   346 NFAEEFTEMDPTYSP--AALPQSSERLFQGYSFVAPSIL 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_001261450.1	PTZ00263	76..397	CDD:140289	173/328 (53%)
S6k	NP_001261450.1	STKc_p70S6K	81..402	CDD:270736	172/328 (52%)
Rps6ka5	NP_001382521.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334261
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1132245at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.850