Protein Alignment S6k and gad8

DIOPT Version :9

• Sequence 1: NP_001261450.1
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_588010.1
• Gene: gad8 / 2539206
• PomBaseID: SPCC24B10.07
• Length: 569
• Species: Schizosaccharomyces pombe
• Alignment Length: 413
• Identity: 172/413 - (41%)
• Similarity: 257/413 - (62%)
• Gaps: 20/413 - (4%)

  Fly     3 DVSDPSELFDLELHDLELQDDKARDSDDDRIELDDVDLEPELCIN--------LHQDTEGQETIQ 59
            |||..|:| .|.:: |.....::|:...:...|..:.|.|...:|        ||..: |:..:|
pombe   153 DVSRYSKL-SLNIY-LRSSSSRSRNGMGNDAFLGGIKLSPSFIVNKLTDEWVPLHGGS-GELRVQ 214

  Fly    60 LCEENVNPGKIKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTA 124
            :..:......:.:..  |||.||:|||.:|||.||||   ||.::.:|:|.:|||.|| ::.:..
pombe   215 MLYKPNQSTPLTIDA--FELLKVVGKGSFGKVMQVRK---RDTSRIYALKTMKKAHIV-SRSEVD 273

  Fly   125 HTRAERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEII 189
            ||.|||.:|..|.:||||.|.::||:.|||||:|.:::|||||.||:|||.|......||::|::
pombe   274 HTLAERTVLAQVNNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELL 338

  Fly   190 LALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTIEYMAPEILTRS 254
            :||..||:..:|||||||||||||..||:.|.||||||.::.:...|:|||||.||:|||:|...
pombe   339 VALECLHEFNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELLLGH 403

  Fly   255 GHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTPEARDLVRRLMKRQEP 319
            |:.|.||||:||.|:::|:||:|||..||..:....||:..|..|..:..:|:||:..|:.|...
pombe   404 GYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAKDLLSGLLTRAPE 468

  Fly   320 QRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTRQIPVDS-PDD 383
            :|||||  .|..::.||||..::|..:.|::::||.||.:.|..|.|.||:.||.:||:|| ..|
pombe   469 KRLGSG--GAQEIKNHPFFDDIDWKKLCAKKIQPPFKPSVESAIDTSNFDSEFTSEIPMDSVVAD 531

  Fly   384 TTLSESANLIFQGFTYVAPSILE 406
            :.|||:....|..::|..|:.::
pombe   532 SHLSETVQQRFANWSYQRPTTID 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_001261450.1	PTZ00263	76..397	CDD:140289	154/321 (48%)
		STKc_p70S6K	81..402	CDD:270736	152/321 (47%)
gad8	NP_588010.1	YPK1_N_like	66..225	CDD:212165	16/74 (22%)
		PTZ00263	214..545	CDD:140289	155/338 (46%)
		STKc_YPK1_like	235..547	CDD:270737	150/317 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0598
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100157
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R469
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740