Protein Alignment S6k and pkg-2

DIOPT Version :10

• Sequence 1: NP_523941.2
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_741467.1
• Gene: pkg-2 / 177659
• WormBaseID: WBGene00015650
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 360
• Identity: 128/360 - (35%)
• Similarity: 188/360 - (52%)
• Gaps: 47/360 - (13%)

  Fly    13 LELHDLELQDDKARDSDDDRIELDDVDLEPELCINLHQDTEGQETIQLCEENVNPGKIKLGPKDF 77
            |:..||   ||:.|......||..||:||                                  |.
 Worm   283 LDTTDL---DDEIRPRASSTIEEADVELE----------------------------------DL 310

  Fly    78 ELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAERNILEAVKHPFIV 142
            :....||.||:|:|..||..:.|.    :|:|::.||.|| ..|..:|..:||.||....:.:||
 Worm   311 QRVSTLGMGGFGRVELVRSASSRT----YALKIMNKAHIV-ETKQESHVVSERRILMQCDNDYIV 370

  Fly   143 ELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALGHLHKLGIIYRDLKP 207
            .:...::...|:|:::|...|||::..|.::|.|..|.|.||.:..:.||.:||:..|:||||||
 Worm   371 RMYKTYRDSEKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFYCAGAMEALEYLHRKNIVYRDLKP 435

  Fly   208 ENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMFDM 272
            ||:|||..|..||.|||..|: ::.|..|.|||||.||:||||:...||..:||.|:||..|.::
 Worm   436 ENMLLDRNGWPKLVDFGFAKK-LKNGGRTWTFCGTAEYVAPEIVLNKGHDLSVDIWALGIFMCEL 499

  Fly   273 LTGVPPFTAENRKKTIETILKA--KLNLPAYLTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQIH 335
            |||.|||::.:...|...|||.  |...|.::|.||.|::..|.|.:..:|||.|  |...::.|
 Worm   500 LTGSPPFSSTDPMVTYNAILKGLEKWAWPRFVTKEAIDMMLSLCKYEPTERLGFG--DIGEIRHH 562

  Fly   336 PFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDT 370
            .:|.:.::....|.|:.||..|.:.::.|.|.|||
 Worm   563 IWFDNFDFVGFRAHRIRPPFIPSVANDIDTSNFDT 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_523941.2	STKc_p70S6K	81..402	CDD:270736	115/292 (39%)
pkg-2	NP_741467.1	CAP_ED	72..173	CDD:237999
		STKc_cGK	316..572	CDD:270724	105/263 (40%)
		S_TK_X	566..617	CDD:214529	10/32 (31%)