Protein Alignment S6k and Sgk2

DIOPT Version :9

• Sequence 1: NP_001261450.1
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_604458.1
• Gene: Sgk2 / 171497
• RGDID: 620232
• Length: 367
• Species: Rattus norvegicus
• Alignment Length: 346
• Identity: 165/346 - (47%)
• Similarity: 221/346 - (63%)
• Gaps: 20/346 - (5%)

  Fly    68 GKIKLGPK--------DFELKKVLGKGGYGKVFQV-RKTAGRDANKYFAMKVLKKASIVTNQKDT 123
            |.|.|||.        ||:..||:|||.||||... ||:.|    .::|:|||:|.||:.| |:.
  Rat    18 GNINLGPSANPNARPTDFDFLKVIGKGNYGKVLLAKRKSDG----AFYAVKVLQKKSILKN-KEQ 77

  Fly   124 AHTRAERNI-LEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSE 187
            :|..||||: |:.|:|||:|.|.|:|||..|||.:|:|::|||||.||:||..|||....||.:|
  Rat    78 SHIMAERNVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQREHRFLEPRARFYTAE 142

  Fly   188 IILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTIEYMAPEILT 252
            :..|:|:||.|.||||||||||||||.||||.|||||||||.::....|.|||||.||:|||:|.
  Rat   143 VASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLR 207

  Fly   253 RSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTPEARDLVRRLMKRQ 317
            :..:.:|||||.|||::::||.|:|||...:..:..|.||...|.:|...|..|.||::.|:.:.
  Rat   208 KEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVAACDLLQGLLHKD 272

  Fly   318 EPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTRQIPVDS-- 380
            :.||||| .||...::.|.||..:||||:..:||.||..|.:....|:..||..||::....|
  Rat   273 QRQRLGS-KEDFLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDPEFTQEAVSKSIG 336

  Fly   381 --PDDTTLSESANLIFQGFTY 399
              ||..:.|..|:..|.||:|
  Rat   337 CTPDTMSSSSGASSAFLGFSY 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_001261450.1	PTZ00263	76..397	CDD:140289	157/326 (48%)
		STKc_p70S6K	81..402	CDD:270736	158/325 (49%)
Sgk2	NP_604458.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		5/9 (56%)
		S_TKc	35..292	CDD:214567	134/262 (51%)
		PKc_like	39..359	CDD:304357	158/325 (49%)
		Nuclear localization signal. /evidence=ECO:0000250	68..77		5/9 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0598
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100157
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.710