Protein Alignment S6k and Gprk1

DIOPT Version :10

• Sequence 1: NP_523941.2
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: XP_061516725.1
• Gene: Gprk1 / 1280643
• VectorBaseID: AGAMI1_009833
• Length: 728
• Species: Anopheles gambiae
• Alignment Length: 453
• Identity: 139/453 - (30%)
• Similarity: 218/453 - (48%)
• Gaps: 59/453 - (13%)

  Fly    53 EGQETIQLCEENVNPGKIKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIV 117
            |..:..:.|:.......|:|...||.:.:::|:||:|:|:..||.   |..|.:|||.|.|..|.
Mosquito   167 ESDKYTRFCQWKNLELNIQLTMNDFSVHRIIGRGGFGEVYGCRKA---DTGKMYAMKCLDKKRIK 228

  Fly   118 TNQKDTAHTRAERNILEAVKH----PFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLE 178
            ..|.:|.... ||.:|..|..    ||||.:.|||.|..||..||:.::||:|..||.:.|:|.|
Mosquito   229 MKQGETLALN-ERTMLSLVSTGVDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFNE 292

  Fly   179 DTTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTI 243
            ....||.:|:||.|.|:||..|:||||||.|||||..|||:::|.||..:..::  ..|...||.
Mosquito   293 SDMKFYAAEVILGLEHMHKRFIVYRDLKPANILLDENGHVRISDLGLACDFSKK--KPHASVGTH 355

  Fly   244 EYMAPEILTR-SGHGKAVDWWSLGALMFDMLTGVPPFTAENRKK---------TIETILKAKLNL 298
            .|||||:|:: :.:..:.||:|.|.:::.:|.|..||.....|.         |::......:.|
Mosquito   356 GYMAPEVLSKGTPYDSSADWFSFGCMLYKLLKGHSPFRQHKTKDKHEIDRMTLTMQPSPLQNVEL 420

  Fly   299 PAYLTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKP---LLR 360
            |...:.|.|||:..|::|...:|||.....|..|:.||||..::|:.|..::..||:.|   .:.
Mosquito   421 PESFSKELRDLLEGLLQRDIDKRLGCKGGGAEEVKCHPFFAGIDWNQVYYQKYTPPLIPPRGEVN 485

  Fly   361 SED--DVSQFDTRFTRQIPVDSPDD-------TTLSES-----ANLIFQGFTYVAPSILEDMHRA 411
            :.|  |:..||...|:.|.:...|.       .|:||.     |..:|:.....|.. ||...:|
Mosquito   486 AADAFDIGSFDEEDTKGIKLTEQDQELYRYFPLTISERWQQEVAETVFETVNTEADK-LEQKRKA 549

  Fly   412 NRMPARSPRRTPRQLPDSSFRLQFPSANVGANAPLAMHGHSQR-SGMFARATPPHHMQTFAPR 473
            .:          :|..|:..:          .:...:||:.:: .|.||......:.:.:..|
Mosquito   550 KQ----------KQRFDADEK----------ESDCILHGYIKKYGGSFASVWQTRYAKLYPNR 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_523941.2	STKc_p70S6K	81..402	CDD:270736	121/351 (34%)
Gprk1	XP_061516725.1	None