Protein Alignment S6k and Akt1

DIOPT Version :10

• Sequence 1: NP_523941.2
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001159366.1
• Gene: Akt1 / 11651
• MGIID: 87986
• Length: 488
• Species: Mus musculus
• Alignment Length: 337
• Identity: 150/337 - (44%)
• Similarity: 213/337 - (63%)
• Gaps: 8/337 - (2%)

  Fly    51 DTEGQETIQLCEENVNPGKIKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKAS 115
            |..|.|.:   |.::...|.::...:||..|:||||.:|||..|::.|   ..:|:|||:|||..
Mouse   127 DNSGAEEM---EVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKA---TGRYYAMKILKKEV 185

  Fly   116 IVTNQKDTAHTRAERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDT 180
            ||. :.:.|||..|..:|:..:|||:..|.|:|||..:|..::||.:|||||.||.||.:|.||.
Mouse   186 IVA-KDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDR 249

  Fly   181 TCFYLSEIILALGHLH-KLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTIE 244
            ..||.:||:.||.:|| :..::|||||.||::||..||:|:||||||||.|::|....|||||.|
Mouse   250 ARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPE 314

  Fly   245 YMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTPEARDL 309
            |:|||:|..:.:|:|||||.||.:|::|:.|..||..::.:|..|.||..::..|..|.|||:.|
Mouse   315 YLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSL 379

  Fly   310 VRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTR 374
            :..|:|:...||||.|.|||..:..|.||.::.|.||..::|.||.||.:.||.|...||..||.
Mouse   380 LSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTA 444

  Fly   375 QIPVDSPDDTTL 386
            |:...:|.|..|
Mouse   445 QMITITPPDQVL 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_523941.2	STKc_p70S6K	81..402	CDD:270736	143/307 (47%)
Akt1	NP_001159366.1	PH_PKB	4..111	CDD:269947
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..137		4/12 (33%)
		STKc_PKB	154..466	CDD:270723	143/307 (47%)