Protein Alignment S6k and Rps6ka3

DIOPT Version :9

• Sequence 1: NP_001261450.1
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_683747.1
• Gene: Rps6ka3 / 110651
• MGIID: 104557
• Length: 740
• Species: Mus musculus
• Alignment Length: 427
• Identity: 196/427 - (45%)
• Similarity: 266/427 - (62%)
• Gaps: 33/427 - (7%)

  Fly     1 MADVSDPSELFDLELHDLELQDDKARDSDDDRIELDDVDLEP--ELCINLHQDTEGQETIQLCEE 63
            :|.::||.:...:|         ...||.::..::.|   ||  |..|| .|..||.........
Mouse     3 LAQLADPWQKMAVE---------SPSDSAENGQQIMD---EPMGEEEIN-PQTEEGSIKEIAITH 54

  Fly    64 NVNPGKIKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRA 128
            :|..|..|..|..|||.||||:|.:||||.|:|.:|.||.:.:||||||||::  ..:|...|:.
Mouse    55 HVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL--KVRDRVRTKM 117

  Fly   129 ERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALG 193
            ||:||..|.|||||:|.|||||:|||||||::|.||:||..|.:|.:|.|:...|||:|:.|||.
Mouse   118 ERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALD 182

  Fly   194 HLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTIEYMAPEILTRSGHGK 258
            |||.||||||||||||||||.:||:|||||||.||.|......::||||:||||||::.|.||.:
Mouse   183 HLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQ 247

  Fly   259 AVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTPEARDLVRRLMKRQEPQRLG 323
            :.||||.|.|||:||||..||..::||:|:..||||||.:|.:|:|||:.|:|.|.||....|||
Mouse   248 SADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLG 312

  Fly   324 SGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTRQIPVDSPDDTTLSE 388
            :||:....::.|.||..::|:.:..|.:.||.||.....:|...||..||.:.|.||| ....|.
Mouse   313 AGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSP-GIPPSA 376

  Fly   389 SANLIFQGFTYVA---------------PSILEDMHR 410
            :|:.:|:||::||               .||::.:||
Mouse   377 NAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQQLHR 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_001261450.1	PTZ00263	76..397	CDD:140289	169/320 (53%)
		STKc_p70S6K	81..402	CDD:270736	170/335 (51%)
Rps6ka3	NP_683747.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41		12/50 (24%)
		STKc_RSK_N	72..388	CDD:270734	168/318 (53%)
		STKc_RSK2_C	402..740	CDD:271078	4/12 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830536
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1132245at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R469
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.880