DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment S6k and rps6ka5

DIOPT Version :9

Sequence 1:	NP_001261450.1	Gene:	S6k / 38654	FlyBaseID:	FBgn0283472	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	XP_002933270.1	Gene:	rps6ka5 / 100489041	XenbaseID:	XB-GENE-950590	Length:	784	Species:	Xenopus tropicalis

Alignment Length:	343	Identity:	178/343 - (51%)
Similarity:	234/343 - (68%)	Gaps:	10/343 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 KLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAERNILEA 135
            |:|.::|||.||||.|.|||||.|||.:|.|:.|.:||||||||:|:...|...|||.||.:||.
Frog    28 KVGLENFELLKVLGTGAYGKVFLVRKISGHDSGKLYAMKVLKKATIIQKAKTAEHTRTERQVLEH 92

  Fly   136 VKH-PFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALGHLHKLG 199
            ::. ||:|.|.||||||.||:|||:|::|||||.||.:...|.|:....|:.||:|||.||||||
Frog    93 IRQSPFLVTLHYAFQTDTKLHLILDYINGGELFTHLSQREKFTENEVLVYIGEIVLALEHLHKLG 157

  Fly   200 IIYRDLKPENILLDAQGHVKLTDFGLCKEHI-QEGIVTHTFCGTIEYMAPEILT--RSGHGKAVD 261
            |||||:|.||||||:.|||.||||||.||.: .|....::||||||||||||:.  .|||.||||
Frog   158 IIYRDIKLENILLDSSGHVVLTDFGLSKEFLSDENERAYSFCGTIEYMAPEIVKGGDSGHDKAVD 222

  Fly   262 WWSLGALMFDMLTGVPPFTAENRKKT----IETILKAKLNLPAYLTPEARDLVRRLMKRQEPQRL 322
            |||||.||:::|||..|||.:..|.:    ...|||::...|..::...:|::|.|:.:...:||
Frog   223 WWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSEAVKDIIRCLLLKDPKKRL 287

  Fly   323 GSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTRQIPVDSPDDTTLS 387
            |.||:....::.|||||..||||:.|:::..|.||:::.|.||..|...||...|..||  ..|.
Frog   288 GCGPDGCDEIKKHPFFKSFNWDDLAAKKIPAPFKPIIKDELDVGNFAEEFTEMDPTYSP--AALP 350

  Fly   388 ESANLIFQGFTYVAPSIL 405
            .:|:.||||:::||||||
Frog   351 MNADRIFQGYSFVAPSIL 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_001261450.1	PTZ00263	76..397	CDD:140289	169/328 (52%)
S6k	NP_001261450.1	STKc_p70S6K	81..402	CDD:270736	168/328 (51%)
rps6ka5	XP_002933270.1	STKc_MSK1_N	33..322	CDD:270764	153/288 (53%)
		S_TK_X	304..364	CDD:214529	24/61 (39%)
		STKc_MSK1_C	403..712	CDD:271081
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1132245at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010