Protein Alignment S6k and rps6ka3b

DIOPT Version :10

• Sequence 1: NP_523941.2
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: XP_009295647.1
• Gene: rps6ka3b / 100009657
• ZFINID: ZDB-GENE-070209-74
• Length: 739
• Species: Danio rerio
• Alignment Length: 398
• Identity: 188/398 - (47%)
• Similarity: 255/398 - (64%)
• Gaps: 32/398 - (8%)

  Fly    39 DLEPELCINLHQDTEGQETIQLCEENVN-----------PGKIKLGPKDFELKKVLGKGGYGKVF 92
            :.||.   ::.:|:.|::....|:|.|:           .|..|..|:.|||:||||:|.:||||
Zfish    21 ETEPH---HVLEDSMGEDENLSCQEEVSVKEINITHLVKEGSEKADPQQFELRKVLGQGSFGKVF 82

  Fly    93 QVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAERNILEAVKHPFIVELVYAFQTDGKLYLI 157
            .|:||.|.||.:.:||||||||::  ..:|...|:.||:||..|.|||||:|.|||||:||||||
Zfish    83 LVKKTTGPDAGQLYAMKVLKKATL--KVRDQVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLI 145

  Fly   158 LEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTD 222
            |::|.||:||..|.:|.:|.|:...|||:|:.|||.|||.||||||||||||||||..||:||||
Zfish   146 LDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDEDGHIKLTD 210

  Fly   223 FGLCKEHIQEGIVTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKT 287
            |||.||.|......::||||:||||||::.|.||..:.||||.|.||::||||..||..::||:|
Zfish   211 FGLSKESIDHENKAYSFCGTVEYMAPEVVNRRGHTYSADWWSYGVLMYEMLTGTLPFQGKDRKET 275

  Fly   288 IETILKAKLNLPAYLTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLE 352
            :..||||||.:|.:|:.||:.|:|.|.||....|||:||:....::.|||:..::|:.:..|...
Zfish   276 MTMILKAKLGMPQFLSSEAQSLLRSLFKRNPTNRLGAGPDGVEEIKRHPFYVSIDWNKLFRRESH 340

  Fly   353 PPIKPLLRSEDDVSQFDTRFTRQIPVDSPDDTTLSESANLIFQGFTYVA---------------P 402
            ||.||.....||...||..||.:.|.||| ....|.:||.:|:||::||               .
Zfish   341 PPFKPATGRPDDTFYFDPEFTAKTPKDSP-GVPPSANANRLFRGFSFVAITSEEESQSLPSNSMS 404

  Fly   403 SILEDMHR 410
            ||::.:||
Zfish   405 SIVQQLHR 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6k	NP_523941.2	STKc_p70S6K	81..402	CDD:270736	171/335 (51%)
rps6ka3b	XP_009295647.1	STKc_RSK_N	71..387	CDD:270734	169/318 (53%)
		Protein Kinases, catalytic domain	403..739	CDD:473864	4/10 (40%)