DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bre1 and PEX10

DIOPT Version :9

Sequence 1:	NP_001286950.1	Gene:	Bre1 / 38652	FlyBaseID:	FBgn0086694	Length:	1044	Species:	Drosophila melanogaster
Sequence 2:	NP_010551.1	Gene:	PEX10 / 851858	SGDID:	S000002673	Length:	337	Species:	Saccharomyces cerevisiae

Alignment Length:	201	Identity:	40/201 - (19%)
Similarity:	71/201 - (35%)	Gaps:	67/201 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   893 LRQQAMEMHKRKAIESAQSAAD---------LKLH---------------------------LEK 921
            |.::.|:.:|...||..:|.|.         |.:|                           |.|
Yeast   126 LYKKIMKNNKESKIEDTESVAAFCKGLLDFILDVHMTLFYFKGAFYSISKRIFGMRYVFKHILSK 190

  Fly   922 YHAQMKE--------------AQQVV---AEKTSSLEAEAYKTKRLQEELAQ----FKRKAER-- 963
            ..|..:|              ||.|:   ...||:|.:..|..||..:.:.:    .:.::|.
Yeast   191 NEANFREEGSQKYKVLGYILLAQNVMKWYPVLTSTLGSWIYGRKRTNDSITRSSVGLQERSEHES 255

  Fly   964 ----MKKMEMSGTTI-DEVMIEEIREYKETLTCPSCKVKRKDAVLSKCFHVFCYDCLRTRYETRQ 1023
                .|:.:::...: |:..:..|.|  .:..|..|.:...|...:.|.|:||:.||.:..:.|.
Yeast   256 IEGIPKESQLTHINLSDKNQLPFIPE--ASRKCILCLMNMSDPSCAPCGHLFCWSCLMSWCKERP 318

  Fly  1024 RKCPKC 1029
             :||.|
Yeast   319 -ECPLC 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bre1	NP_001286950.1	SMC_prok_B	<235..987	CDD:274008	27/157 (17%)
		AAA_23	<654..762	CDD:290211
		zf-C3HC4_2	991..1029	CDD:290634	12/37 (32%)
PEX10	NP_010551.1	PEX10	5..337	CDD:227861	40/201 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R146
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030