Protein Alignment Bre1 and rnf20

DIOPT Version :9

• Sequence 1: NP_001286950.1
• Gene: Bre1 / 38652
• FlyBaseID: FBgn0086694
• Length: 1044
• Species: Drosophila melanogaster
• Sequence 2: XP_002941911.2
• Gene: rnf20 / 779468
• XenbaseID: XB-GENE-5746936
• Length: 965
• Species: Xenopus tropicalis
• Alignment Length: 1076
• Identity: 440/1076 - (40%)
• Similarity: 629/1076 - (58%)
• Gaps: 159/1076 - (14%)

  Fly    11 GSSCLVAAAAAGQPPIKKVHFEPH-------LIGPVSTLEEMDIKVLEFQNKKLAQRIEQRMRTE 68
            ||...|....:..||.||...|..       .:|.||:.||.|::.|:.:|||||..::||...|
 Frog     5 GSKRTVGDVGSLGPPEKKAAVEDSGTTVETIKLGSVSSTEEQDLRTLQLKNKKLAGMLDQRQAIE 69

  Fly    69 AELRHRIEQLEKRQTQDDAVLNVVNRYWNQLNEDIRVLLQRFDAE-------------------- 113
            .|||.|||.||:||..|||.|.::||||:|.:|:|.:.|.|:|.:
 Frog    70 DELRDRIETLERRQATDDASLLIINRYWSQFDENIGIFLGRYDLDQDLGEFLTERKALVLPEPEP 134

  Fly   114 TADELENRNEN-------EVTTSFLAQLSTWDKEELDEKLANRVQVSKRAVAKIVQVIDRLMQRN 171
            .:|....|.||       |...||||.|::...||::.:|..||:.|:|||::||.|.|||   :
 Frog   135 DSDSNPERKENERGEGLWEAPLSFLATLASSSSEEIESQLQERVESSRRAVSRIVLVYDRL---H 196

  Fly   172 EKITHVLKGDSLASAGSGSGAGAGGEEEQQQASGDAETTTSSAGVHALEETLKQTHIEIMSENHK 236
            :::.|:.|                              ..:|.....:||.::..:..:.:||.:
 Frog   197 DQLDHLAK------------------------------KLNSTDPSHVEEAVRDLNSLLSNENAR 231

  Fly   237 LQNLNTSLHEKFHTMSLKMKEYQDAHTAKETENAELKNQIDELQYDLEKIHCRNDKLENHLAEAI 301
            ||.:...|.||...||.:..:.|....:.|:....|...|::||:|::||..|..:|..||:|.:
 Frog   232 LQEICNLLQEKQQNMSQEFLQLQSRLESAESRVLVLDGHIEDLQWDIDKIRKREQRLNRHLSEVL 296

  Fly   302 EKL--KAYHQIYGDPNKSTNSAKTPTTTGSG--GATTSVNSQLLEELQKELEEYRELANNRLQEL 362
            |::  |.| ::||              .||.  |.|.::||:..||:..|::..:|||.||||||
 Frog   297 ERVNSKGY-KVYG--------------AGSSLYGGTITINSRKFEEMTSEVDLNKELAVNRLQEL 346

  Fly   363 DKLHATHRETLKEVEKLKMDIRQLPESVIVETTEYKCLQSQFSVLYNESMQIKTMLDETRNQLQT 427
            :||....:|...|.:.|:.::....|..:..:.||:|:|||||||||||:|:||.|||.|:.|..
 Frog   347 EKLRQDLQEVTSENQDLQAELASAVEENVRLSPEYRCMQSQFSVLYNESLQLKTQLDEARSLLHG 411

  Fly   428 SKNQHLRQIEVMESEELIAQKKVRSEMIQMEDVLALIRKEYETLRIEFEQNMAANEQTAPINREM 492
            :::.|.||:|::|.:|:..|||||:|:||:||.||.:|||||.|||||||.:|||||..||||||
 Frog   412 TRSNHQRQLELIERDEISLQKKVRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAANEQAGPINREM 476

  Fly   493 RHLITSLQNHNGQLKGEVQRYKRKYKDTSTDNLKLRQELADALATLEGNKLQAATGAAGEEIKQE 557
            ||||:||||||.||||||.||||:.::...|..|:|...:.:|..|........|.....|||.|
 Frog   477 RHLISSLQNHNHQLKGEVLRYKRRLREIQGDISKMRSRSSSSLFLLPSQSSTEDTREETAEIKTE 541

  Fly   558 NSTGVKEENSNNVSASGQTNQTNSGNDTNVAIKEENHISAEDEADDEASGKDVKDGIKQEKLSSG 622
                 .|:.:.|.||..|         ..|..|.|.              ::|:..::|.:....
 Frog   542 -----PEDTTTNASALSQ---------PEVVPKREE--------------EEVQPPLQQPQRDRR 578

  Fly   623 DAAAAEKKDSPGPGNSTSSATNSVPVKNEKDSKDGVKGK-----DVKAVESETVRDLKAQLKKAL 682
            :.....::|.                ..||:..|..|.|     |.|..|:|||:.:||:||:..
 Frog   579 ERERERERDR----------------GREKERGDTSKEKPKHEADTKRKEAETVKQMKAELKRVQ 627

  Fly   683 NDQKEMKLLLDMYKGVSKDQRDKVQLMATEKKLRSEIEELRQQLKKLQESKREERKKLADEEALR 747
            ...::||||||||:...|:|||||||||.|||.::|:||||.:|::|:|.:|.:.||:|||:|||
 Frog   628 ESLRDMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEELRLRLRELEERERRDSKKMADEDALR 692

  Fly   748 KIKQLEEQKYELQKQMANHKPTDNSWGSGAPGTANYTRPFVGSHEEEALLNEMEVTGQAFEDMQE 812
            :::..|||...|||:::                       |...||||||:||:|||||||||||
 Frog   693 RMRTAEEQTEVLQKRLS-----------------------VAKQEEEALLSEMDVTGQAFEDMQE 734

  Fly   813 QNSRLIQQLREKDDANFKLMSERIKANQLHKLLREEKTVLEDQMATATTQIEAMHIVLRKLEEKE 877
            ||.||:|||||||||||||||||||:||:||||:|||..|.||:.|..||::|...|||||||||
 Frog   735 QNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQLLTLRTQVDAQLQVLRKLEEKE 799

  Fly   878 RSLQATVASIEKELMLRQQAMEMHKRKAIESAQSAADLKLHLEKYHAQMKEAQQVVAEKTSSLEA 942
            ..||:::.:.||||.||.||:::.|||..||:|.|.:|:..||....::::.::.:.|.:||.|.
 Frog   800 HLLQSSINTGEKELALRTQALDLCKRKTTESSQQAEELRAQLELSQKKLQDLREEIIENSSSREK 864

  Fly   943 EAYKTKRLQEELAQFKRKAERMKKMEMSGTTIDEVMIEEIREYKETLTCPSCKVKRKDAVLSKCF 1007
            :|:..||.||::::.::|.|..||.::. .|.|::::|||:|||..||||.|..::.||||:|||
 Frog   865 DAFNYKRAQEDISRLRKKLESTKKPDLV-PTCDKILMEEIKEYKARLTCPCCNSRKMDAVLTKCF 928

  Fly  1008 HVFCYDCLRTRYETRQRKCPKCNCAFGANDYHRLYL 1043
            ||||::|::|||:||||||||||.||||||:||:|:
 Frog   929 HVFCFECVKTRYDTRQRKCPKCNAAFGANDFHRIYI 964

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bre1	NP_001286950.1	SMC_prok_B	<235..987	CDD:274008	321/760 (42%)
		AAA_23	<654..762	CDD:290211	56/112 (50%)
		zf-C3HC4_2	991..1029	CDD:290634	25/37 (68%)
rnf20	XP_002941911.2	RING_Ubox	909..963	CDD:418438	38/53 (72%)
		Smc	<45..372	CDD:224117	116/374 (31%)
		PTZ00121	<321..907	CDD:173412	290/653 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	696	1.000	Domainoid score	I127
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	797	1.000	Inparanoid score	I494
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D139233at33208
OrthoFinder	1	1.000	-	-		FOG0001777
OrthoInspector	1	1.000	-	-		otm48650
Panther	1	1.100	-	-	O	PTHR23163
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R146
SonicParanoid	1	1.000	-	-		X1307
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.100