Protein Alignment Bre1 and PEX10

DIOPT Version :9

• Sequence 1: NP_001286950.1
• Gene: Bre1 / 38652
• FlyBaseID: FBgn0086694
• Length: 1044
• Species: Drosophila melanogaster
• Sequence 2: NP_722540.1
• Gene: PEX10 / 5192
• HGNCID: 8851
• Length: 346
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 83/402 - (20%)
• Similarity: 130/402 - (32%)
• Gaps: 148/402 - (36%)

  Fly   676 AQLKKALNDQKEMKLLLDM-YKG--------------VSKDQRDKVQLMATEKKLRSEIEELRQQ 725
            |..:|.|..:||::||.|: |.|              ||..|.|..::.......|..:..|...
Human    37 AGARKWLEWRKEVELLSDVAYFGLTTLAGYQTLGEEYVSIIQVDPSRIHVPSSLRRGVLVTLHAV 101

  Fly   726 LKKLQESKREERKKLADEEALRKIKQLEEQKYELQKQMANHKPTDNSWGSGAPGTANYTRPFVGS 790
            |..|.            ::||..::|      |||....:.:|...|.|.|..|.:. .|.::..
Human   102 LPYLL------------DKALLPLEQ------ELQADPDSGRPLQGSLGPGGRGCSG-ARRWMRH 147

  Fly   791 H-------EEEALLNEMEVTGQAFEDMQEQN--------------SRL----IQQLREKDDANFK 830
            |       :..|||..:.|..|....:|..:              .||    .|.||  .|....
Human   148 HTATLTEQQRRALLRAVFVLRQGLACLQRLHVAWFYIHGVFYHLAKRLTGITYQALR--PDPLRV 210

  Fly   831 LMSERIKANQLHKLLREEKTVLEDQMATATTQ----IEAMHIVLRKLEEKERSLQATVASIEKEL 891
            |||....|.|    ||......||..|..:.:    |..:|:||        |:...:....:
Human   211 LMSVAPSALQ----LRVRSLPGEDLRARVSYRLLGVISLLHLVL--------SMGLQLYGFRQ-- 261

  Fly   892 MLRQQAMEMHKRKAIESAQSAADLKLHLEKYHAQMKEAQQVVAEKTSSLEAEAYKTKRLQEELAQ 956
              ||:|     ||         :.:||            :.::.:.:|||..|.....|
Human   262 --RQRA-----RK---------EWRLH------------RGLSHRRASLEERAVSRNPL------ 292

  Fly   957 FKRKAERMKKMEMSGTTIDEVMIEEIREYKETLTCPSCKVKRKDAVLSKCFHVFCYDCLRTRYET 1021
                                              |..|..:|:....:.|.|:||::|: |.:.:
Human   293 ----------------------------------CTLCLEERRHPTATPCGHLFCWECI-TAWCS 322

  Fly  1022 RQRKCPKCNCAF 1033
            .:.:||.|...|
Human   323 SKAECPLCREKF 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bre1	NP_001286950.1	SMC_prok_B	<235..987	CDD:274008	70/354 (20%)
		AAA_23	<654..762	CDD:290211	24/100 (24%)
		zf-C3HC4_2	991..1029	CDD:290634	11/37 (30%)
PEX10	NP_722540.1	Pex2_Pex12	18..263	CDD:282595	58/262 (22%)
		RING	293..334	CDD:238093	12/41 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R146
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940