DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bre1 and Pex10

DIOPT Version :9

Sequence 1:	NP_001286950.1	Gene:	Bre1 / 38652	FlyBaseID:	FBgn0086694	Length:	1044	Species:	Drosophila melanogaster
Sequence 2:	NP_001261265.1	Gene:	Pex10 / 38182	FlyBaseID:	FBgn0035233	Length:	299	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	55/277 - (19%)
Similarity:	107/277 - (38%)	Gaps:	70/277 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   812 EQNSRLIQQLREKDDANFKLMSER--IKANQLHKLLRE-----------EKTVLEDQMATATTQI 863
            ::::|...:|.|......:|...|  ||.||:.:||.|           .:|:.|:.  |...|:
  Fly    18 QKDARYTNELAEDLSDVLRLTGPRNWIKYNQMCRLLAELSYHGFASANNLQTLGEEY--TGIIQV 80

  Fly   864 EAMHIVLRKLEEKERSLQATVASIEKELMLRQQAMEMHKRKAIESAQSAADLKLHLEKYHAQMKE 928
            :..:   :::..:...|.|.|.....: .|.|:.|:........:.:...::|..|:|...::::
  Fly    81 DGNY---KQIPSRLLQLIAIVLEFGGD-SLFQRLMQKLDTYVANNDEIRTEIKPQLKKIIQRLRQ 141

  Fly   929 AQQVVAEKTSS---LEAEAYK-TKR------------LQEELAQF-------------------- 957
            :...|.....|   |:|..|: :||            ||.|.:.:
  Fly   142 SPSYVKALHKSLFYLDASKYQLSKRTTGINYVLIRHWLQPEFSLYGYKILGVITFLQVSVSLAIS 206

  Fly   958 ------KRKAERMKKMEMSGTTIDEVMIEEIREYKE----TLTCPSCKVKRKDAVLSKCFHVFCY 1012
                  :.|.::::.::.:|..    .::.....|:    |..|..|...|.|:.|:.|.|:||:
  Fly   207 GWDAWREHKRQQLESIKQAGKN----FLQRSSSTKDVDPNTPQCILCLEPRSDSSLTPCGHIFCW 267

  Fly  1013 DCLRTRYETRQRKCPKC 1029
            .||....|.|. :||.|
  Fly   268 SCLLEWLEERD-ECPLC 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bre1	NP_001286950.1	SMC_prok_B	<235..987	CDD:274008	37/229 (16%)
		AAA_23	<654..762	CDD:290211
		zf-C3HC4_2	991..1029	CDD:290634	15/37 (41%)
Pex10	NP_001261265.1	Pex2_Pex12	20..>173	CDD:282595	32/158 (20%)
Pex10	NP_001261265.1	zf-RING_2	244..284	CDD:290367	16/41 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R146
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.030