Protein Alignment Cralbp and TTPA

DIOPT Version :10

• Sequence 1: NP_523939.1
• Gene: Cralbp / 38651
• FlyBaseID: FBgn0035636
• Length: 324
• Species: Drosophila melanogaster
• Sequence 2: NP_001400347.1
• Gene: TTPA / 7274
• HGNCID: 12404
• Length: 317
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 67/272 - (24%)
• Similarity: 116/272 - (42%)
• Gaps: 47/272 - (17%)

  Fly    54 DTFLLRFLRAKKFSVPMAEQTLLKYLNIRRTFPHMSTQLDYLEPR--LGDLIDQGYIFAVPQRDK 116
            |:||||||||:.|.:.:|.:.|..|...|...|.:|..   |.||  :| |:..||...:..||.
Human    49 DSFLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISAD---LHPRSIIG-LLKAGYHGVLRSRDP 109

  Fly   117 HGRRVVVINAKGL---------------------------------------NPKIHTSCDQAKA 142
            .|.:|::...:..                                       :||:.|:.|..:.
Human   110 TGSKVLIYRIESCSVAQAGEQWAISTHYNLCLPSSSDSPASASQVAGTTAHWDPKVFTAYDVFRV 174

  Fly   143 HFLTYECLMEDQETQITGLTHVGDFAGVTTAHVTNWNPTEFARIFKWGEQSLPMRHKEIHLINVP 207
            ..:|.|.::::.|||..|:..:.|..|...:|.....|:...:|......|.|::.:.|||||.|
Human   175 SLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEP 239

  Fly   208 STLKWLIDFVKNRVSSKMKNRLIIYGSE-KELMKSVDQGCLPLEMGG-KVPMREMIELWKQELAT 270
            .....:...:|..::.|:|.|:.::|:. |:.:.......||||.|| :..|.::.:.|...:..
Human   240 VIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFPDILPLEYGGEEFSMEDICQEWTNFIMK 304

  Fly   271 KRDLILGLDKSI 282
            ..|.:..:.:||
Human   305 SEDYLSSISESI 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cralbp	NP_523939.1	CRAL_TRIO_N	31..78	CDD:215024	12/23 (52%)
		SEC14	106..254	CDD:469559	41/188 (22%)
TTPA	NP_001400347.1	CRAL_TRIO_N	<40..73	CDD:215024	12/23 (52%)
		CRAL_TRIO	159..286	CDD:459890	33/126 (26%)