DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cralbp and sec14l7

DIOPT Version :9

Sequence 1:	NP_523939.1	Gene:	Cralbp / 38651	FlyBaseID:	FBgn0035636	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_009303977.1	Gene:	sec14l7 / 566865	ZFINID:	ZDB-GENE-141216-145	Length:	405	Species:	Danio rerio

Alignment Length:	310	Identity:	78/310 - (25%)
Similarity:	132/310 - (42%)	Gaps:	67/310 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ALLKIAKRELREDRCTREQSLEQLRNWVAKNEDL--QNVRCDDTFLLRFLRAKKFSVPMAEQTLL 76
            ||:..||...|....:.:|: |.|..:..|.||:  |.....|.:|||:|||:.|:||.||..|.
Zfish     7 ALIYSAKMSGRVGDLSPKQA-EALTQFREKLEDVWDQLSNQTDHYLLRWLRARTFNVPKAEAMLR 70

  Fly    77 KYLNIRRTFPHMSTQL---DYLEPRLGDLIDQ-------GYIFAVPQRDKHGRRVVVINAKGLNP 131
            |:|..||   ||..:.   |:..|   :::::       ||       |:.|..:.......|:|
Zfish    71 KHLEFRR---HMKLETIIDDWSPP---EVLERYVAGGMCGY-------DREGSPIWFDIIGPLDP 122

  Fly   132 K------IHTSCDQAK---AHFLTYECLMEDQE--TQITGLTHVGDFAGVTTAHVTNWNPT--EF 183
            |      ....|.:.|   |..|..||..:.::  ..|..:|.:.|..|:...|:  |.|.  .:
Zfish   123 KGLLLSASKQDCLRTKIRDAELLRRECEKQSKKLGKHIESITIIYDCEGLGMKHL--WKPAVEMY 185

  Fly   184 ARIFKWGEQSLPMRHKEIHLINVPSTLKWLIDFVKNRVSSKMKNRLIIYGSE-KELMKS-VDQGC 246
            ..|....|::.|...|::.||..|.......:.||:.:..:.:.::.:.||. |:::|: ||...
Zfish   186 GEILTMYEENYPESLKKVLLIKAPKLFPIAYNLVKHFLREETRQKIAVLGSNWKDVLKNYVDADQ 250

  Fly   247 LP-------------------LEMGGKVP----MREMIEL-WKQELATKR 272
            :|                   |..||.||    :|:.|:: ::|.:...|
Zfish   251 IPAAYGGSLTDPDGNPLCTTMLRYGGVVPKSYYVRDSIKVQYEQNITISR 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cralbp	NP_523939.1	CRAL_TRIO_N	31..78	CDD:215024	20/48 (42%)
Cralbp	NP_523939.1	SEC14	101..254	CDD:238099	38/193 (20%)
sec14l7	XP_009303977.1	CRAL_TRIO_N	26..72	CDD:215024	19/46 (41%)
		CRAL_TRIO	97..258	CDD:279044	36/169 (21%)
		GOLD_2	317..395	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910