DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cralbp and Sec14l4

DIOPT Version :9

Sequence 1:	NP_523939.1	Gene:	Cralbp / 38651	FlyBaseID:	FBgn0035636	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001102560.1	Gene:	Sec14l4 / 498399	RGDID:	1565810	Length:	412	Species:	Rattus norvegicus

Alignment Length:	263	Identity:	58/263 - (22%)
Similarity:	109/263 - (41%)	Gaps:	70/263 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 REQSLEQLRNWVAKNEDLQNV-----RCDDTFLLRFLRAKKFSVPMAEQTLLKYLNIRRTFPHMS 89
            ::::|.:.|      |.||:|     :.||.||||:|||:.|.:..:|..|.|::..|.     .
  Rat    12 QQEALTRFR------EILQDVLPTLPKADDFFLLRWLRARNFDLKKSEDMLRKHVEFRN-----Q 65

  Fly    90 TQLDYL---EP-------------------------RLGDLIDQGYIFAVPQRDKHGRRVVVINA 126
            ..||::   :|                         .:|.|..:|...:..::|...:|:.|
  Rat    66 QDLDHILTWQPPEVIRLYDSGGLCGYDYEGCPVWFDLIGTLDPKGLFMSASKQDLIRKRIKV--- 127

  Fly   127 KGLNPKIHTSCDQAKAHFLTYECLMEDQE--TQITGLTHVGDFAGVTTAHVTNWNPT--EFARIF 187
                      |:     .|.:||.::.|:  .::..:..|.|..|::..|:  |.|.  .:.:.|
  Rat   128 ----------CE-----MLLHECELQSQKLGRKVERMVMVFDMEGLSLRHL--WKPAVEVYQQFF 175

  Fly   188 KWGEQSLPMRHKEIHLINVPSTLKWLIDFVKNRVSSKMKNRLIIYGS--EKELMKSVDQGCLPLE 250
            ...|.:.|...|.:.:|..|.......:.||:.:....:.:::|.|.  ::||:|.:....||:|
  Rat   176 AILEANYPETVKNLIVIRAPKLFPVAFNLVKSFIGEVTQKKIVILGGNWKQELLKFMSPDQLPVE 240

  Fly   251 MGG 253
            .||
  Rat   241 FGG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cralbp	NP_523939.1	CRAL_TRIO_N	31..78	CDD:215024	18/51 (35%)
Cralbp	NP_523939.1	SEC14	101..254	CDD:238099	34/159 (21%)
Sec14l4	NP_001102560.1	CRAL_TRIO_N	13..59	CDD:215024	18/51 (35%)
		SEC14	76..244	CDD:214706	36/188 (19%)
		GOLD_2	284..379	CDD:404736
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900