DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cralbp and Ku80

DIOPT Version :9

Sequence 1:	NP_523939.1	Gene:	Cralbp / 38651	FlyBaseID:	FBgn0035636	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_609767.2	Gene:	Ku80 / 34930	FlyBaseID:	FBgn0041627	Length:	699	Species:	Drosophila melanogaster

Alignment Length:	298	Identity:	58/298 - (19%)
Similarity:	118/298 - (39%)	Gaps:	63/298 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TTGLPEALLKIAK--RELREDR--CTREQSLEQLRNWVAKNEDLQNVRCDDTFLLRFLRAKKFSV 68
            |....|..||.||  .|:.:|:  |.|:..:    ::|....|...::.:|.       :....:
  Fly    16 TCAAEEVKLKSAKCVAEILKDKIVCDRKDYV----SFVLVGCDTDEIKTEDA-------SHPNVL 69

  Fly    69 PMAE------QTLLKYLN-IRRTFPHMSTQLDYLEPRLGDLIDQGYIFAVPQRDKHGRRVVVINA 126
            |..|      |.||::.. :.:|.......|:.|:..| :|.:......|.:     ||::::..
  Fly    70 PFGEPRLCSWQLLLEFFQFVNKTACEDGEWLNGLQAAL-ELQNVATTLRVAR-----RRILLLFD 128

  Fly   127 KGLNPKIHTSCDQAKAHFLTYECLMEDQETQITGLTHVGDFAGVTTAHVTNWNPTEFARIFKWGE 191
            ....|:     |..|.:.:|.|.|.|:.|. |.| ||       ..|::.|...::...||.:..
  Fly   129 FNDFPQ-----DYEKFNEITDELLGENIEL-IVG-TH-------NIAYIDNAITSQPQAIFNFSR 179

  Fly   192 QSLP--MRHKEIHLINVPSTLKWLIDFVK--NRVSSKMKNRLIIYGSEKELMKSVD---QGCLPL 249
            :..|  :.:::..|..||.....|..|.:  :.|......|..::.::..:...:.   ||.  :
  Fly   180 KCGPDELNNQKYALSLVPRCNATLCSFKEALHTVFKVTNRRPWVWNAKLNIGSKISISLQGI--I 242

  Fly   250 EMGGKVPMREMIELWKQELATKRDLILGLDKSILRSDR 287
            .|..:.|:: ::::|.::           |:.::|..|
  Fly   243 AMKNQTPVK-LVKVWAEK-----------DEIVIRETR 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cralbp	NP_523939.1	CRAL_TRIO_N	31..78	CDD:215024	8/52 (15%)
Cralbp	NP_523939.1	SEC14	101..254	CDD:238099	31/159 (19%)
Ku80	NP_609767.2	Ku_N	7..213	CDD:281693	48/227 (21%)
		KU80	221..524	CDD:238445	8/62 (13%)
		Ku_PK_bind	562..663	CDD:285938
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900