DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cralbp and Ttpa

DIOPT Version :9

Sequence 1:	NP_523939.1	Gene:	Cralbp / 38651	FlyBaseID:	FBgn0035636	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_037180.1	Gene:	Ttpa / 25571	RGDID:	3915	Length:	278	Species:	Rattus norvegicus

Alignment Length:	233	Identity:	67/233 - (28%)
Similarity:	113/233 - (48%)	Gaps:	8/233 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 DTFLLRFLRAKKFSVPMAEQTLLKYLNIRRTFPHMSTQLDYLEPR--LGDLIDQGYIFAVPQRDK 116
            |.||||||||:.|.:.:|.:.:..|...|...|.:|..   |.||  || |:..||...:..||.
  Rat    49 DAFLLRFLRARDFDLDLAWRLMKNYYKWRAECPELSAD---LHPRSILG-LLKAGYHGVLRSRDP 109

  Fly   117 HGRRVVVINAKGLNPKIHTSCDQAKAHFLTYECLMEDQETQITGLTHVGDFAGVTTAHVTNWNPT 181
            .|.||::......:||:.|:.|..:...:|.|.::::.|||..|:..:.|..|...:|.....|:
  Rat   110 TGSRVLIYRISYWDPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQISHAFQITPS 174

  Fly   182 EFARIFKWGEQSLPMRHKEIHLINVPSTLKWLIDFVKNRVSSKMKNRLIIYGSE-KELMKSVDQG 245
            ...:|......|.|::.:.|||||.|.....:...:|..::.|:|.|:.::|:. |..:......
  Rat   175 VAKKIAAVVTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKGRIHLHGNNYKSSLLQHFPD 239

  Fly   246 CLPLEMGG-KVPMREMIELWKQELATKRDLILGLDKSI 282
            .||||.|| :..|.::.:.|...:....|.:..:.::|
  Rat   240 ILPLEYGGNESSMEDICQEWTNFIMKSEDYLSSISETI 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cralbp	NP_523939.1	CRAL_TRIO_N	31..78	CDD:215024	11/23 (48%)
Cralbp	NP_523939.1	SEC14	101..254	CDD:238099	43/154 (28%)
Ttpa	NP_037180.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		CRAL_TRIO_N	25..73	CDD:215024	11/23 (48%)
		CRAL_TRIO	99..248	CDD:395525	41/148 (28%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	190..192		0/1 (0%)
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	208..211		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820