Protein Alignment Cralbp and SEC14L2

DIOPT Version :10

• Sequence 1: NP_523939.1
• Gene: Cralbp / 38651
• FlyBaseID: FBgn0035636
• Length: 324
• Species: Drosophila melanogaster
• Sequence 2: NP_036561.1
• Gene: SEC14L2 / 23541
• HGNCID: 10699
• Length: 403
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 55/262 - (20%)
• Similarity: 108/262 - (41%)
• Gaps: 68/262 - (25%)

  Fly    30 REQSLEQLRNWVAKNEDLQNV-----RCDDTFLLRFLRAKKFSVPMAEQTLLKYLNIRRTFPHMS 89
            ::::|.:.|      |::|:|     ..||.||||:|||:.|.:..:|..|.|::..|:. ..:.
Human    12 QKEALAKFR------ENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQ-KDID 69

  Fly    90 TQLDYLEPR------------------------LGDLIDQGYIFAVPQRDKHGRRVVVINAKGLN 130
            ..:.:..|.                        :|.|..:|.:|:..::|.            |.
Human    70 NIISWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL------------LR 122

  Fly   131 PKIHTSCDQAKAHFLTYECLMEDQE--TQITGLTHVGDFAGVTTAHVTNWNPT-----EFARIFK 188
            .|:. .|:     .|..||..:..:  .::..:|.:.|..|:...|:  |.|.     ||..:|
Human   123 TKMR-ECE-----LLLQECAHQTTKLGRKVETITIIYDCEGLGLKHL--WKPAVEAYGEFLCMF- 178

  Fly   189 WGEQSLPMRHKEIHLINVPSTLKWLIDFVKNRVSSKMKNRLIIYGSE-KE-LMKSVDQGCLPLEM 251
              |::.|...|.:.::..|.......:.:|..:|...:.::::.|:. || |:|.:....:|:|.
Human   179 --EENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVEY 241

  Fly   252 GG 253
            ||
Human   242 GG 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cralbp	NP_523939.1	CRAL_TRIO_N	31..78	CDD:215024	17/51 (33%)
		SEC14	106..254	CDD:469559	33/157 (21%)
SEC14L2	NP_036561.1	CRAL_TRIO_N	13..59	CDD:215024	17/51 (33%)
		SEC14	76..244	CDD:214706	36/191 (19%)