DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cralbp and Clvs2

DIOPT Version :9

Sequence 1:	NP_523939.1	Gene:	Cralbp / 38651	FlyBaseID:	FBgn0035636	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_780657.1	Gene:	Clvs2 / 215890	MGIID:	2443223	Length:	327	Species:	Mus musculus

Alignment Length:	260	Identity:	70/260 - (26%)
Similarity:	123/260 - (47%)	Gaps:	2/260 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GLPEALLKIAKRELREDRCTREQSLEQLRNWVAKNEDLQNVRCDDTFLLRFLRAKKFSVPMAEQT 74
            ||....|:.|:.||.|:..|..|.::::|:.|....|:..:|.||.|:||||||:||....|.:.
Mouse     7 GLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRL 71

  Fly    75 LLKYLNIRRTFPHMSTQLDYLEPRLGDLIDQGYIFAVPQRDKHGRRVVVINAKGLNPKIHTSCDQ 139
            |.:|...|:....|.......:|.:...:..|:...:...|.:||:::|:.|...:...:|..|.
Mouse    72 LAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDI 136

  Fly   140 AKAHFLTYECLMEDQETQITGLTHVGDFAGVTTAHVTNWNPTEFARIFKWGEQSLPMRHKEIHLI 204
            .:|..|:.|.::||.|.|:.|...:.|::..|....:...|.......:..:.|.|.|...||.:
Mouse   137 LRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPNMLRLAIEGLQDSFPARFGGIHFV 201

  Fly   205 NVPSTLKWLIDFVKNRVSSKMKNRLIIYGSE-KELMKSVDQGCLPLEMGGKVPMREMIELWKQEL 268
            |.|..:..|...::..:..|.:.|:.::|:. ..|.:.:....||.|.||.:|..:| ..|.:.|
Mouse   202 NQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDM-GTWARTL 265

Fly 269 268
Mouse 266 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cralbp	NP_523939.1	CRAL_TRIO_N	31..78	CDD:215024	18/46 (39%)
Cralbp	NP_523939.1	SEC14	101..254	CDD:238099	35/153 (23%)
Clvs2	NP_780657.1	CRAL_TRIO_N	29..75	CDD:215024	18/45 (40%)
		SEC14	106..251	CDD:238099	33/144 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4417
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8767
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.970