DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cralbp and Sec14l4

DIOPT Version :9

Sequence 1:	NP_523939.1	Gene:	Cralbp / 38651	FlyBaseID:	FBgn0035636	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_666125.1	Gene:	Sec14l4 / 103655	MGIID:	2144095	Length:	403	Species:	Mus musculus

Alignment Length:	259	Identity:	58/259 - (22%)
Similarity:	109/259 - (42%)	Gaps:	62/259 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 REQSLEQLRNWVAKNEDLQNV-----RCDDTFLLRFLRAKKFSVPMAEQTLLKYLNIRRTFPHMS 89
            ::::|.:.|      |.||::     :.||.||||:|||:.|.:..:|..|.|::..|.. .::.
Mouse    12 QQEALARFR------ETLQDLLPTLPKADDYFLLRWLRARNFDLKKSEDMLRKHVEFRNQ-QNLD 69

  Fly    90 TQLDYLEPRLGDLID------------------------QGYIFAVPQRDKHGRRVVVINAKGLN 130
            ..|.:..|.:..|.|                        :|...:..::|...:|:.|
Mouse    70 QILTWQAPEVIQLYDSGGLSGYDYEGCPVWFDIIGTMDPKGLFMSASKQDMIRKRIKV------- 127

  Fly   131 PKIHTSCDQAKAHFLTYECLMEDQE--TQITGLTHVGDFAGVTTAHVTNWNPT--EFARIFKWGE 191
                  |:     .|.:||.::.|:  .:|..:..|.|..|::..|:  |.|.  .:.:.|...|
Mouse   128 ------CE-----MLLHECELQSQKLGRKIERMVMVFDMEGLSLRHL--WKPAVEVYQQFFAILE 179

  Fly   192 QSLPMRHKEIHLINVPSTLKWLIDFVKNRVSSKMKNRLIIYGS--EKELMKSVDQGCLPLEMGG 253
            .:.|...|.:.:|..|.......:.||:.:..:.:.:::|.|.  ::||:|.|....||:|.||
Mouse   180 ANYPETVKNLIIIRAPKLFPVAFNLVKSFMGEETQKKIVILGGNWKQELVKFVSPDQLPVEFGG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cralbp	NP_523939.1	CRAL_TRIO_N	31..78	CDD:215024	17/51 (33%)
Cralbp	NP_523939.1	SEC14	101..254	CDD:238099	37/183 (20%)
Sec14l4	NP_666125.1	CRAL_TRIO_N	13..59	CDD:215024	17/51 (33%)
		SEC14	77..244	CDD:214706	38/187 (20%)
		GOLD_2	284..379	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2738
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760