DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Myt1 and YDA

DIOPT Version :9

Sequence 1:	NP_647987.2	Gene:	Myt1 / 38649	FlyBaseID:	FBgn0040298	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001319310.1	Gene:	YDA / 842674	AraportID:	AT1G63700	Length:	883	Species:	Arabidopsis thaliana

Alignment Length:	567	Identity:	125/567 - (22%)
Similarity:	224/567 - (39%)	Gaps:	172/567 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EKHHRLPLPELHDDKHRHKQCNGENSNRFRPPKYKTRGYVAVDNNNLNRSQSLGSCSTNSSQIAH 66
            ::.||||||.|                             .:.|          :|..:.:..|
plant   353 QQSHRLPLPPL-----------------------------LISN----------TCPFSPTYSA- 377

  Fly    67 AISFRDAGCSDSSTLPSSPVQAELSTLSLSHFEQCFERLAKLGEGSFGEVFQVRDRSDGQLYAVK 131
                     :.|.::|.||.:||.:....|.:::  .||  ||.||||.|:...:...|::.|:|
plant   378 ---------ATSPSVPRSPARAEATVSPGSRWKK--GRL--LGMGSFGHVYLGFNSESGEMCAMK 429

  Fly   132 -------------ISKQLFRGEQYRAERLEEVRRYEEFSGHENCIRFIRAWEQYDRLYMQME-LC 182
                         .::||  |::...  |..:|       |:|.:::..:....|:||:.:| :.
plant   430 EVTLCSDDPKSRESAQQL--GQEISV--LSRLR-------HQNIVQYYGSETVDDKLYIYLEYVS 483

  Fly   183 RESLEQYLLRCQRIPEERIWHILLDLLRGLKSLHDRNLIHLDIKLDNVLIGEDDETCKLADFGLV 247
            ..|:.:.|....:..|..|.:....:|.||..||.:|.:|.|||..|:|: :.....|:||||:.
plant   484 GGSIYKLLQEYGQFGENAIRNYTQQILSGLAYLHAKNTVHRDIKGANILV-DPHGRVKVADFGMA 547

  Fly   248 IDVDRANSHHATEGDSRYMAPEILQGH--FSKAADIFSLGIAMLELACYMDLPSNGPLWHELRHG 310
            ..:...:...:.:|...:||||:::..  .:.|.||:|||..:||:|      :..|.|.:. .|
plant   548 KHITAQSGPLSFKGSPYWMAPEVIKNSNGSNLAVDIWSLGCTVLEMA------TTKPPWSQY-EG 605

  Fly   311 I-----------LPEEFINKISLELQSVIKSMMKPDPAQRPTAEQLLSHPKLQYLQKKRKSLMN- 363
            :           || :..:.:|.|.:..::..::.:||.||||.|||.|..::.:....:.:::
plant   606 VPAMFKIGNSKELP-DIPDHLSEEGKDFVRKCLQRNPANRPTAAQLLDHAFVRNVMPMERPIVSG 669

  Fly   364 -----FSMLSRSFRRSRRAVWGRMCNWKTAAFRYLLYFLEVLHL-CKPITASQPNINI------- 415
                 .::.|.:.|.                       |::.|. ..|...|:...|.
plant   670 EPAEAMNVASSTMRS-----------------------LDIGHARSLPCLDSEDATNYQQKGLKH 711

  Fly   416 -----VPSSPSSKGVPLVPQVEFQLVGSTPIANRDCYASDFLSG-EDPLDLSNQGSPNVI--NST 472
                 :..||.:...|:.|      ||| ||.:..   |..:|| ..|..:|   ||:.:  :||
plant   712 GSGFSISQSPRNMSCPISP------VGS-PIFHSH---SPHISGRRSPSPIS---SPHALSGSST 763

  Fly   473 PLN--------TNQGKSRLDLLKNNVDSM------GRYVHVHDFESP 505
            ||.        .:|.::.::.|...:.|.      |.:.....|:.|
plant   764 PLTGCGGAIPFHHQRQTTVNFLHEGIGSSRSPGSGGNFYTNSFFQEP 810

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	74/275 (27%)
Myt1	NP_647987.2	Pkinase	102..349	CDD:278497	74/273 (27%)
YDA	NP_001319310.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910