DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Myt1 and Ulk3

DIOPT Version :9

Sequence 1:	NP_647987.2	Gene:	Myt1 / 38649	FlyBaseID:	FBgn0040298	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001258064.1	Gene:	Ulk3 / 691171	RGDID:	1587417	Length:	472	Species:	Rattus norvegicus

Alignment Length:	263	Identity:	61/263 - (23%)
Similarity:	119/263 - (45%)	Gaps:	33/263 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 KLGEGSFGEVFQV-RDRSDGQLYAVK-----------ISKQLFRGEQYRAERLEEVRRYEEFSGH 159
            :||.|::..|::. ..::..::.|:|           :...|...|..:..|...:.:.::|.
  Rat    19 RLGSGTYATVYKAYAKKATREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQ-- 81

  Fly   160 ENCIRFIRAWEQYDRLYMQMELCRESLEQYLLRCQRIPEERIWHILL-DLLRGLKSLHDRNLIHL 223
                     |:. |.:|:.||.|........:..:||..|::..:.: .|...|:.||:||:.||
  Rat    82 ---------WDN-DNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHL 136

  Fly   224 DIKLDNVLIGE-DDETCKLADFGLVIDVDRANSHHATEGDSRYMAPE-ILQGHFSKAADIFSLGI 286
            |:|..|:|:.. :....||||||....:...:..|...|...||||| :.:..:....|::|:|:
  Rat   137 DLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCRRQYDARVDLWSVGV 201

  Fly   287 AMLELACYMDLPSNGPLWHELRHGILPEEFIN-----KISLELQSVIKSMMKPDPAQRPTAEQLL 346
            .:.| |.:...|.....:.||...|.....|.     ::||:.:.:::.:::.||:.|.:.:...
  Rat   202 ILYE-ALFGQPPFASRSFSELEEKIRSNRVIELPLRPQLSLDCRDLLQRLLERDPSHRISFQDFF 265

  Fly   347 SHP 349
            :||
  Rat   266 AHP 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	59/261 (23%)
Myt1	NP_647987.2	Pkinase	102..349	CDD:278497	59/261 (23%)
Ulk3	NP_001258064.1	S_TKc	14..270	CDD:214567	61/263 (23%)
		STKc_ULK3	18..269	CDD:271023	61/263 (23%)
		MIT_2	279..353	CDD:239147
		MIT	374..449	CDD:294211
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910