DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myt1 and Stk4

DIOPT Version :9

Sequence 1:	NP_647987.2	Gene:	Myt1 / 38649	FlyBaseID:	FBgn0040298	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_067395.1	Gene:	Stk4 / 58231	MGIID:	1929004	Length:	487	Species:	Mus musculus

Alignment Length:	303	Identity:	91/303 - (30%)
Similarity:	139/303 - (45%)	Gaps:	71/303 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 DSSTLPSSPVQAELSTLSLSHFEQCFERLAKLGEGSFGEVFQVRDRSDGQLYAVKISKQLFRGEQ 141
            |..:|...|             |:.|:.|.||||||:|.|::...:..||:.|:|         |
Mouse    18 DEDSLTKQP-------------EEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIK---------Q 60

  Fly   142 YRAER-LEEVRRYEEFSGHENC-----IRFIRAWEQYDRLYMQMELC-RESLEQYL-LRCQRIPE 198
            ...|. |:|:  .:|.|..:.|     :::..::.:...|::.||.| ..|:...: ||.:.:.|
Mouse    61 VPVESDLQEI--IKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTE 123

  Fly   199 ERIWHILLDLLRGLKSLHDRNLIHLDIKLDNVLIGEDDETCKLADFGLVIDV-DRANSHHATEGD 262
            :.|..||...|:||:.||....||.|||..|:|:..:.. .||||||:...: |.....:...|.
Mouse   124 DEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGH-AKLADFGVAGQLTDTMAKRNTVIGT 187

  Fly   263 SRYMAPEILQG-HFSKAADIFSLGIAMLELA----CYMD---------LPSNGP-------LWHE 306
            ..:||||::|. .::..|||:||||..:|:|    .|.|         :|:|.|       ||.:
Mouse   188 PFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSD 252

  Fly   307 LRHGILPEEFINKISLELQSVIKSMMKPDPAQRPTAEQLLSHP 349
                       |.:....|.::||     |.||.||.|||.||
Mouse   253 -----------NFMDFVKQCLVKS-----PEQRATATQLLQHP 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	85/278 (31%)
Myt1	NP_647987.2	Pkinase	102..349	CDD:278497	85/276 (31%)
Stk4	NP_067395.1	STKc_MST1_2	26..281	CDD:132943	89/295 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..334
		Mst1_SARAH	433..480	CDD:314497
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910